Evidence map›Paper›PMID 34992152›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

The Impact of Semiautomatic Segmentation Methods on Metabolic Tumor Volume, Intensity, and Dissemination Radiomics in

Julia Driessen, Gerben J C Zwezerijnen, Heiko Schöder, Esther E E Drees, Marie José Kersten, Alison J Moskowitz, Craig H Moskowitz, Jakoba J Eertink, Henrica C W de Vet, Otto S Hoekstra and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 52 citations in OpenAlex.

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  6. Japanese journal of radiology · 2026
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  12. Predictive value of maximum tumor dissemination (Dmax) in lymphoma patients treated with CD19-specific CAR T-Cells.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
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  13. Role ofTranslational cancer research · 2025
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  18. BaselineClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  19. Baseline [BMC cancer · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Julia DriessenDepartment of Hematology, Amsterdam UMC, University of Amsterdam, LYMMCARE (Lymphoma and Myeloma Center, Amsterdam), Cancer Center Amsterdam, Amsterdam, The Netherlands.
Gerben J C ZwezerijnenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Heiko SchöderDepartment of Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Esther E E DreesDepartment of Pathology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Marie José KerstenDepartment of Hematology, Amsterdam UMC, University of Amsterdam, LYMMCARE (Lymphoma and Myeloma Center, Amsterdam), Cancer Center Amsterdam, Amsterdam, The Netherlands.
Alison J MoskowitzDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Craig H MoskowitzDepartment of Medicine, Sylvester Comprehensive Cancer Center, Miami, Florida.
Jakoba J EertinkDepartment of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands; and.
Henrica C W de VetDepartment of Epidemiology and Data Science, Amsterdam Public Health research institute, Amsterdam, Netherlands.
Otto S HoekstraDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Josée M ZijlstraDepartment of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands; and.
Ronald BoellaardDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands; r.boellaard@amsterdamumc.nl.
Vrije Universiteit Amsterdam · NLAmsterdam University Medical Centers · NLMemorial Sloan Kettering Cancer Center · USUniversity of Amsterdam · NLAmsterdam Neuroscience · NLPublic Health Service of Amsterdam · NLSylvester Comprehensive Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Consensus about a standard segmentation method to derive metabolic tumor volume (MTV) in classical Hodgkin lymphoma (cHL) is lacking, and it is unknown how different segmentation methods influence quantitative PET features. Therefore, we aimed to evaluate the delineation and completeness of lesion selection and the need for manual adaptation with different segmentation methods, and to assess the influence of segmentation methods on the prognostic value of MTV, intensity, and dissemination radiomics features in cHL patients.

Indexed as

Fluorodeoxyglucose F18Hodgkin DiseaseHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRetrospective StudiesTumor BurdenFluorodeoxyglucose F1818F-FDG PET/CTHodgkin lymphomaoutcome predictionradiomicssegmentation methods

Identifiers

PMID34992152
PMCPMC9454468
OpenAlexW4205302318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.