Evidence map›Paper›PMID 34992140›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Deconstructing

Christian Schöne, Anja Poehlein, Nico Jehmlich, Norman Adlung, Rolf Daniel, Martin von Bergen, Silvan Scheller, Michael Rother

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
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  13. Ferredoxin reduction by hydrogen with iron functions as an evolutionary precursor of flavin-based electron bifurcation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Pyruvate-dependent growth ofJournal of bacteriology · 2024
    Article
  15. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Christian SchöneInstitute of Microbiology, Technische Universität Dresden, 01062 Dresden, Germany.ORCID 0000-0002-3999-0406
Anja PoehleinInstitute of Microbiology and Genetics, Georg-August-Universität Göttingen, 37077 Göttingen, Germany.
Nico JehmlichDepartment of Molecular Systems Biology, Helmholtz Centre for Environmental Research, 04318 Leipzig, Germany.ORCID 0000-0002-5638-6868
Norman AdlungDepartment of Bioproducts and Biosystems, Aalto University, 02150 Espoo, Finland.ORCID 0000-0002-4871-7970
Rolf DanielInstitute of Microbiology and Genetics, Georg-August-Universität Göttingen, 37077 Göttingen, Germany.ORCID 0000-0002-8646-7925
Martin von BergenDepartment of Molecular Systems Biology, Helmholtz Centre for Environmental Research, 04318 Leipzig, Germany.ORCID 0000-0003-2732-2977
Silvan SchellerDepartment of Bioproducts and Biosystems, Aalto University, 02150 Espoo, Finland.ORCID 0000-0002-0667-9224
Michael RotherInstitute of Microbiology, Technische Universität Dresden, 01062 Dresden, Germany; michael.rother@tu-dresden.de.ORCID 0000-0002-2306-8783
Aalto University · FIHelmholtz Centre for Environmental Research · DETechnische Universität Dresden · DEUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reductive acetyl-coenzyme A (acetyl-CoA) pathway, whereby carbon dioxide is sequentially reduced to acetyl-CoA via coenzyme-bound C1 intermediates, is the only autotrophic pathway that can at the same time be the means for energy conservation. A conceptually similar metabolism and a key process in the global carbon cycle is methanogenesis, the biogenic formation of methane. All known methanogenic archaea depend on methanogenesis to sustain growth and use the reductive acetyl-CoA pathway for autotrophic carbon fixation. Here, we converted a methanogen into an acetogen and show that

Indexed as

Acetyl Coenzyme AArchaeaCarbon DioxideCarbon MonoxideGenomeMethaneMethanomicrobiaceaeMethanosarcinaProteomeAcetyl Coenzyme ACarbon DioxideCarbon MonoxideMethaneProteomeacetogenicacetyl-CoA pathwaymethanogenicMethanosarcina

Identifiers

PMID34992140
PMCPMC8764690
OpenAlexW4205598697

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.