Evidence map›Paper›PMID 34992127›Full record

ArticleAJNR. American journal of neuroradiology2022

Thin-Slice Pituitary MRI with Deep Learning-Based Reconstruction for Preoperative Prediction of Cavernous Sinus Invasion by Pituitary Adenoma: A Prospective Study.

M Kim, H S Kim, J E Park, S Y Park, Y-H Kim, S J Kim, J Lee, M R Lebel

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04268251 (Prospective MRI Evaluation of Cavernous Sinus Invasion by Pituitary Adenoma Using Deep Learning Based Denoising), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04268251 nacompletednot on this map

Prospective MRI Evaluation of Cavernous Sinus Invasion by Pituitary Adenoma Using Deep Learning Based Denoising

TypeinterventionalSponsorAsan Medical CenterRan2020 to 2022Enrolled67ConditionsCavernous Sinus Invasion by Pituitary AdenomaArmsMRI with deep learning based denoising
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Application of Deep Learning-Based Reconstruction to Magnetic Resonance Imaging of Canine Stifle Joint in Healthy Beagles: Achieving Enhanced Image Quality With Reduced Slice Thickness.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026
    Article
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  7. Improved Assessment of Juxtacortical Lesions in Multiple Sclerosis Using Highly-accelerated High-resolution Double Inversion Recovery MR Imaging with Deep Learning-based Reconstruction.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  8. Article
  9. Identification of the Distal Dural Ring Using Three-dimensional Motion-sensitized Driven-equilibrium Prepared TMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
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  10. Review
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  15. Article
  16. Thin-slice Two-dimensional T2-weighted Imaging with Deep Learning-based Reconstruction: Improved Lesion Detection in the Brain of Patients with Multiple Sclerosis.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 5 countries.

M KimFrom the Department of Radiology and Research Institute of Radiology (M.K., H.S.K., J.E.P., S.J.K.).ORCID 0000-0002-5382-9360
H S KimFrom the Department of Radiology and Research Institute of Radiology (M.K., H.S.K., J.E.P., S.J.K.) radhskim@gmail.com.ORCID 0000-0002-9477-7421
J E ParkFrom the Department of Radiology and Research Institute of Radiology (M.K., H.S.K., J.E.P., S.J.K.).ORCID 0000-0002-4419-4682
S Y ParkDepartments of Clinical Epidemiology and Biostatistics (S.Y.P.).ORCID 0000-0002-2702-1536
Y-H KimNeurosurgery (Y.-H.K.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0002-8852-6503
S J KimFrom the Department of Radiology and Research Institute of Radiology (M.K., H.S.K., J.E.P., S.J.K.).ORCID 0000-0001-7070-7333
J LeeGE Healthcare (J.L.), Seoul, Korea.ORCID 0000-0002-0164-1139
M R LebelGE Healthcare (M.R.L.), Calgary, Alberta, Canada.ORCID 0000-0002-7526-9974
Research Institute of Radiology · BYCancer Research And Biostatistics · USGeneral Electric (Spain) · ESUniversity of Calgary · CAUniversity of Ulsan · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAccurate radiologic prediction of cavernous sinus invasion by pituitary adenoma remains challenging. We aimed to assess whether 1-mm-slice-thickness MRI with deep learning-based reconstruction can better predict cavernous sinus invasion by pituitary adenoma preoperatively and to estimate the depth of invasion and degree of contact in relation to the carotid artery, compared with 3-mm-slice-thickness MRI. MATERIALS AND

methodsThis single-institution, prospective study included 67 consecutive patients (mean age, 53 [SD, 12] years; 28 women), between January and August 2020, who underwent a combined contrast-enhanced T1-weighted imaging protocol of 1-mm-slice-thickness MRI + deep learning-based reconstruction and 3-mm-slice-thickness MRI. An expert neuroradiologist who was blinded to the imaging protocol determined cavernous sinus invasion using the modified Knosp classification on 1-mm-slice-thickness MRI + deep learning-based reconstruction and 3-mm-slice-thickness MRI, respectively. Reference standards were established by the consensus of radiologic, intraoperative, pathologic, and laboratory findings. The primary end point was the diagnostic performance of each imaging protocol, and the secondary end points included depth of invasion and degree of contact in relation to the carotid artery.

resultsThe diagnostic performance of 1-mm-slice-thickness MRI + deep learning-based reconstruction (area under the curve, 0.79; 95% CI, 0.69 - 0.89) in predicting cavernous sinus invasion by pituitary adenoma was higher than that of 3-mm-slice-thickness MRI (area under the curve, 0.61; 95% CI, 0.52-0.70;

conclusionsCompared with 3-mm-slice-thickness MRI, 1-mm-slice-thickness MRI + deep learning-based reconstruction showed a higher diagnostic performance in preoperatively predicting cavernous sinus invasion by pituitary adenomas and demonstrated a greater depth and degree of contact in relation to the carotid artery.

Indexed as

Cavernous SinusDeep LearningPituitary NeoplasmsFemaleHumansMagnetic Resonance ImagingMiddle AgedNeoplasm InvasivenessProspective Studies

Identifiers

PMID34992127
PMCPMC8985667
OpenAlexW4206228264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.