Evidence map›Paper›PMID 34992126›Full record

ArticleAJNR. American journal of neuroradiology2022

Morphologic Variants of the Hand Motor Cortex in Developing Brains from Neonates through Childhood Assessed by MR Imaging.

F Wu, H Zhao, Y Zhang, M Wang, C Liu, X Wang, Y Cheng, C Jin, J Yang, X Li

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PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

F WuFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0003-1414-9896
H ZhaoFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-8435-8805
Y ZhangFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-3464-3907
M WangFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-0852-8753
C LiuFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-5797-7862
X WangFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0003-3781-5150
Y ChengFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-8911-5829
C JinFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-5761-341X
J YangFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0003-4250-1391
X LiFrom the Department of Radiology (F.W., H.Z., Y.Z., M.W., C.L., X.W., Y.C., C.J., J.Y., X.L.), the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China xianj.li@mail.xjtu.edu.cn.ORCID 0000-0001-7690-9155

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeKnowledge of anatomic markers of the hand motor cortex is essential in the evaluation and treatment of motor neurologic diseases for both adults and developing populations. However, hand motor cortex variants in developing brains remain to be investigated. Our objective was to observe morphologic variants of the hand motor cortex in developing brains from neonates through childhood. MATERIALS AND

methodsIn this study, 542 participants (0∼15 years of age) were retrospectively enrolled and divided into different age groups. The hand motor cortex morphology was evaluated on the basis of 3D T1WI. Variations in hand motor cortex variants were compared among different age groups. Inter-gender and interhemispheric differences of hand motor cortex variants were also evaluated.

resultsVarious hand motor cortex variants could be observed in developing brains, even in the neonatal period. One new morphologic shape, "immature Ω," was found in neonates and infants. The proportion of this new shape decreased dramatically during the first year after birth, then disappeared after 1 year of age. It persisted for a longer time in the right hemisphere and in males. However, sex or hemispheric effects on the distribution of the proportion of variants were not statistically significant. Furthermore, the proportion of concordance of the bilateral hand motor cortex showed an increasing trend with age (

conclusionsVarious hand motor cortex variants already existed at birth. The distribution of proportions of different variants developmentally varied during the first year after birth and became stable after 1 year of age. The concordance of the bilateral hand motor cortex could be influenced by age and sex.

Indexed as

Motor CortexAdultBrainChildFemaleFunctional LateralityHandHumansInfant, NewbornMagnetic Resonance ImagingMaleRetrospective Studies

Identifiers

PMID34992126
PMCPMC8985685

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