Evidence map›Paper›PMID 34992104›Full record

ArticleBMJ open2022

Association between initial opioid prescription diagnosis type and subsequent chronic prescription opioid use in Rhode Island: a population-based cohort study.

Benjamin D Hallowell, Laura C Chambers, Luke Barre, Nancy Diao, Collette Onyejekwe, Alexandra Banks, Jeffery Bratberg, Heidi Weidele, Samara Viner-Brown, James McDonald

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Benjamin D HallowellRhode Island Department of Health, Providence, Rhode Island, USA benjamin.hallowell@health.ri.gov.ORCID 0000-0002-6943-9615
Laura C ChambersRhode Island Department of Health, Providence, Rhode Island, USA.
Luke BarreRoger Williams Medical Center, Providence, Rhode Island, USA.
Nancy DiaoRhode Island Department of Health, Providence, Rhode Island, USA.
Collette OnyejekweRhode Island Department of Health, Providence, Rhode Island, USA.
Alexandra BanksSchool of Public Health, Brown University, Providence, Rhode Island, USA.
Jeffery BratbergCollege of Pharmacy, University of Rhode Island, Kingston, Rhode Island, USA.
Heidi WeideleRhode Island Department of Health, Providence, Rhode Island, USA.
Samara Viner-BrownRhode Island Department of Health, Providence, Rhode Island, USA.
James McDonaldRhode Island Department of Health, Providence, Rhode Island, USA.
Rhode Island Department of Health · USBrown University · USRoger Williams Medical Center · USUniversity of Rhode Island · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify initial diagnoses associated with elevated risk of chronic prescription opioid use.

designPopulation-based, retrospective cohort study.

settingState of Rhode Island.

participantsRhode Island residents with an initial opioid prescription dispensed between 1 April 2019 and 31 March 2020. PRIMARY OUTCOME MEASURE: Subsequent chronic prescription opioid use, defined as receiving 60 or more days' supply of opioids in the 90 days following an initial opioid prescription.

resultsAmong the 87 055 patients with an initial opioid prescription, 3199 (3.7%) subsequently became chronic users. Patients who become chronic users tended to receive a longer days' supply, greater quantity dispensed, but a lower morphine milligram equivalents on the initial opioid prescription. Patients prescribed an initial opioid prescription for diseases of the musculoskeletal system and connective tissue (adjusted OR (aOR): 5.9, 95% CI: 4.7 to 7.6), diseases of the nervous system (aOR: 6.3, 95% CI: 4.9 to 8.0) and neoplasms (aOR: 5.6, 95% CI: 4.2 to 7.5) had higher odds of subsequent chronic prescription opioid use, compared with a referent group that included all diagnosis types with fewer than 15 chronic opioid users, after adjusting for confounders.

conclusionsBy focusing interventions and prescribing guidelines on specific types of diagnoses that carry a high risk of chronic prescription opioid use and diagnoses that would benefit equally or more from alternative management approaches, states and healthcare organisations may more efficiently decrease inappropriate opioid prescribing while improving the quality of patient care.

Indexed as

Analgesics, OpioidPractice Patterns, Physicians'Cohort StudiesDrug PrescriptionsHumansRetrospective StudiesRhode IslandAnalgesics, Opioidclinical pharmacologyepidemiologypain managementpublic health

Identifiers

PMID34992104
PMCPMC8739418
OpenAlexW4205900379

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.