Evidence map›Paper›PMID 34992097›Full record

Observational studyBMJ open2022

Does adherence to a quality indicator regarding early weaning from invasive ventilation improve economic outcome? A single-centre retrospective study.

Alexander Zuber, Oliver Kumpf, Claudia Spies, Moritz Höft, Marc Deffland, Robert Ahlborn, Jochen Kruppa, Roland Jochem, Felix Balzer

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander ZuberInstitute of Medical Informatics, Charité Universitätsmedizin Berlin, Berlin, Germany.
Oliver KumpfDepartment of Anesthesiology and Operative Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Claudia SpiesDepartment of Anesthesiology and Operative Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-1062-0495
Moritz HöftDepartment of Anesthesiology and Operative Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Marc DefflandDepartment of Anesthesiology and Operative Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Robert AhlbornIT Department, Charité Universitätsmedizin Berlin, Berlin, Germany.
Jochen KruppaInstitute of Medical Informatics, Charité Universitätsmedizin Berlin, Berlin, Germany.
Roland JochemDepartments of Machine Tools and Factory Management, TU Berlin, Berlin, Germany.
Felix BalzerInstitute of Medical Informatics, Charité Universitätsmedizin Berlin, Berlin, Germany felix.balzer@charite.de.ORCID 0000-0002-6789-8471

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo measure and assess the economic impact of adherence to a single quality indicator (QI) regarding weaning from invasive ventilation.

designRetrospective observational single-centre study, based on electronic medical and administrative records.

settingIntensive care unit (ICU) of a German university hospital, reference centre for acute respiratory distress syndrome.

participantsRecords of 3063 consecutive mechanically ventilated patients admitted to the ICU between 2012 and 2017 were extracted, of whom 583 were eligible adults for further analysis. Patients' weaning protocols were evaluated for daily adherence to quality standards until ICU discharge. Patients with <65% compliance were assigned to the low adherence group (LAG), patients with ≥65% to the high adherence group (HAG). PRIMARY AND SECONDARY OUTCOME MEASURES: Economic healthcare costs, clinical outcomes and patients' characteristics.

resultsThe LAG consisted of 378 patients with a median negative economic results of -€3969, HAG of 205 (-€1030), respectively (p<0.001). Median duration of ventilation was 476 (248; 769) hours in the LAG and 389 (247; 608) hours in the HAG (p<0.001). Length of stay (LOS) in the LAG on ICU was 21 (12; 35) days and 16 (11; 25) days in the HAG (p<0.001). LOS in the hospital was 36 (22; 61) days in the LAG, and within the HAG, respectively, 26 (18; 48) days (p=0.001).

conclusionsHigh adherence to this single QI is associated with better clinical outcome and improved economic returns. Therefore, the results support the adherence to QI. However, the examined QI does not influence economic outcome as the decisive factor.

Indexed as

Noninvasive VentilationAdultHumansQuality Indicators, Health CareRespiration, ArtificialRetrospective StudiesVentilator Weaninghealth economicsintensive & critical carequality in health care

Identifiers

PMID34992097
PMCPMC8739420

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.