Evidence map›Paper›PMID 34991698›Full record

ArticleSystematic reviews2022

Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis.

Amit Lampit, Nathalie H Launder, Ruth Minkov, Alice Rollini, Christopher G Davey, Carsten Finke, Nicola T Lautenschlager, Hanna Malmberg Gavelin

Open access · goldAbstract read
In one paragraph

Article in Systematic reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Bidirectional causal association between frailty and six psychiatric disorders.European archives of psychiatry and clinical neuroscience · 2026
    Article
  2. Article
  3. Review
  4. Effect of cognitive retraining treatment in mild to moderate depressive disorders.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2023
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Amit LampitDepartment of Psychiatry, University of Melbourne, Parkville, Australia. amit.lampit@unimelb.edu.au.ORCID 0000-0001-6522-8397
Nathalie H LaunderDepartment of Psychiatry, University of Melbourne, Parkville, Australia.
Ruth MinkovDepartment of Psychiatry, University of Melbourne, Parkville, Australia.
Alice RolliniDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Christopher G DaveyDepartment of Psychiatry, University of Melbourne, Parkville, Australia.
Carsten FinkeDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Nicola T LautenschlagerDepartment of Psychiatry, University of Melbourne, Parkville, Australia.
Hanna Malmberg GavelinDepartment of Psychiatry, University of Melbourne, Parkville, Australia.
The University of Melbourne · AUHumboldt-Universität zu Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with depression often present with concurrent cognitive impairment. Computerized cognitive training (CCT) is a safe and efficacious strategy to maintain or enhance cognitive performance in a range of clinical populations. However, its efficacy in people with depression and how it varies across populations and design factors are currently unclear.

methodsWe searched MEDLINE, EMBASE, and PsycINFO from inception to 13 July 2021 for randomised controlled trials examining the efficacy of CCT vs any control condition on cognitive, mood, psychiatric symptoms, psychosocial, and daily functioning in adults with depression. Eligible samples include studies specifically targeting people with major depressive disorder as well as those with other diagnoses where at least 50% of the sample meets the clinical criteria for depression, with the exception of major psychiatric disorders or dementia. The primary outcome is change in the overall cognitive performance. Multivariate analyses will be used to examine the effect sizes on each outcome category as well as possible effect modifiers and correlations between categories. The risk of bias will be assessed using the Cochrane risk of bias tool version 2. DISCUSSION: To the best of our knowledge, this will be the first systematic review and meta-analysis of narrowly defined CCT across clinical populations with depression. We aim to investigate not only whether CCT is efficacious for cognition, but also how such effects vary across design factors, what other clinically relevant outcomes might respond to CCT, and the extent to which they differ across populations. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020204209.

Indexed as

Major Depressive DisorderAdultCognitionDepressionHumansMeta-Analysis as TopicSystematic Reviews as TopicComputerised cognitive trainingDepressionMajor depressive disorderMeta-analysis

Identifiers

PMID34991698
PMCPMC8740357
OpenAlexW4220799225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.