Evidence map›Paper›PMID 34991692›Full record

ArticleTrials2022

ABBaH teens: Activity Breaks for Brain Health in adolescents: study protocol for a randomized crossover trial.

Emerald G Heiland, Karin Kjellenberg, Olga Tarassova, Maria Fernström, Gisela Nyberg, Maria M Ekblom, Björg Helgadottir, Örjan Ekblom

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04552626 (Acute Effects From Prolonged Inactivity and Physical Activity Interventions on Cortical Blood Flow and Arterials Stiffness in School-aged Adolescents.), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04552626 nacompletednot on this map

Acute Effects From Prolonged Inactivity and Physical Activity Interventions on Cortical Blood Flow and Arterials Stiffness in School-aged Adolescents.

TypeinterventionalSponsorThe Swedish School of Sport and Health SciencesRan2020 to 2020Enrolled17ConditionsHealthy AdolescentsArmsProlonged sitting (social breaks), Prolonged sitting with step-up exercise break, Prolonged sitting with simple resistance activity breaks
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Emerald G HeilandDepartment of Physical Activity and Health, The Swedish School of Sport and Health Sciences (GIH), Lidingövägen 1, 11433, Stockholm, Sweden. emerald.heiland@gih.se.ORCID http://orcid.org/0000-0001-7175-0093
Karin KjellenbergDepartment of Physical Activity and Health, The Swedish School of Sport and Health Sciences (GIH), Lidingövägen 1, 11433, Stockholm, Sweden.
Olga TarassovaDepartment of Physiology, Nutrition, and Biomechanics, The Swedish School of Sport and Health Sciences (GIH), Lidingövägen 1, 11433, Stockholm, Sweden.
Maria FernströmDepartment of Physical Activity and Health, The Swedish School of Sport and Health Sciences (GIH), Lidingövägen 1, 11433, Stockholm, Sweden.
Gisela NybergDepartment of Physical Activity and Health, The Swedish School of Sport and Health Sciences (GIH), Lidingövägen 1, 11433, Stockholm, Sweden.
Maria M EkblomDepartment of Physical Activity and Health, The Swedish School of Sport and Health Sciences (GIH), Lidingövägen 1, 11433, Stockholm, Sweden.
Björg HelgadottirDepartment of Physical Activity and Health, The Swedish School of Sport and Health Sciences (GIH), Lidingövägen 1, 11433, Stockholm, Sweden.
Örjan EkblomDepartment of Physical Activity and Health, The Swedish School of Sport and Health Sciences (GIH), Lidingövägen 1, 11433, Stockholm, Sweden.
Swedish School of Sport and Health Sciences · SEKarolinska Institutet · SEPublic Health Agency of Sweden · SEUppsala University · SE

Funding

Stiftelsen för Kunskaps- och Kompetensutveckling 20160040
6 · The paper itself

Abstract

backgroundPhysical activity breaks are widely being implemented in school settings as a solution to increase academic performance and reduce sitting time. However, the underlying physiological mechanisms suggested to improve cognitive function from physical activity and the frequency, intensity, and duration of the breaks remain unknown. This study will investigate the effects of frequent, short physical activity breaks during prolonged sitting on task-related prefrontal cerebral blood flow, cognitive performance, and psychological factors. Additionally, the moderating and mediating effects of arterial stiffness on changes in cerebral blood flow will be tested.

methodsThis is a protocol for a randomized crossover study that will recruit 16 adolescents (13-14 years old). Participants will undergo three different conditions in a randomized order, on three separate days, involving sitting 80 min with a different type of break every 17 min for 3 min. The breaks will consist of (1) seated social breaks, (2) simple resistance activities, and (3) step-up activities. Before and after the 80-min conditions, prefrontal cerebral blood flow changes will be measured using functional near-infrared spectroscopy (primary outcome), while performing working memory tasks (1-, 2-, and 3-back tests). Arterial stiffness (augmentation index and pulse wave velocity) and psychological factors will also be assessed pre and post the 80-min interventions. DISCUSSION: Publication of this protocol will help to increase rigor in science. The results will inform regarding the underlying mechanisms driving the association between physical activity breaks and cognitive performance. This information can be used for designing effective and feasible interventions to be implemented in schools.

trial registrationwww.ClinicalTrials.gov , NCT04552626 . Retrospectively registered on September 21, 2020.

Indexed as

Pulse Wave AnalysisSedentary BehaviorAdolescentBrainCross-Over StudiesExerciseHumansRandomized Controlled Trials as TopicCerebral blood flowCognitive functionfNIRSPhysical activity breaksSedentary

Identifiers

PMID34991692
PMCPMC8733916
OpenAlexW4205692020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.