Evidence map›Paper›PMID 34991688›Full record

ArticleTrials2022

DUbbing Language-therapy CINEma-based in Aphasia post-Stroke (DULCINEA): study protocol for a randomized crossover pilot trial.

Blanca Fuentes, Lydia de la Fuente-Gómez, Cristian Sempere-Iborra, Celia Delgado-Fernández, Aida Tarifa-Rodríguez, María Alonso de Leciñana, Elena de Celis-Ruiz, Raquel Gutiérrez-Zúñiga, José López-Tàppero, Marta Martín Alonso and 8 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04289493 (DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04289493 nacompletednot on this map

DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke (DULCINEA). A Feasibility Cross-over Pilot-trial

TypeinterventionalSponsorInstituto de Investigación Hospital Universitario La PazRan2020 to 2024Enrolled44ConditionsAphasia, Post-IctalArmsLanguage and functional communication therapy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Blanca Fuentes *Department of Neurology and Stroke Center, La Paz University Hospital, Department of Medicine, Neurosciences Unit, Universidad Autónoma de Madrid, IdiPAZ Institute for Health Research, Madrid, Spain. blanca.fuentes@salud.madrid.org.
Lydia de la Fuente-GómezNeurosciences Area, IdiPAZ Institute for Health Research, Madrid, Spain.
Cristian Sempere-IborraNeurosciences Area, IdiPAZ Institute for Health Research, Madrid, Spain.
Celia Delgado-FernándezNeurosciences Area, IdiPAZ Institute for Health Research, Madrid, Spain.
Aida Tarifa-RodríguezDepartment of Psychology, Universidad Autónoma de Madrid, Madrid, Spain.
María Alonso de LeciñanaDepartment of Neurology and Stroke Center, La Paz University Hospital, Department of Medicine, Neurosciences Unit, Universidad Autónoma de Madrid, IdiPAZ Institute for Health Research, Madrid, Spain.
Elena de Celis-RuizDepartment of Neurology and Stroke Center, La Paz University Hospital, Department of Medicine, Neurosciences Unit, Universidad Autónoma de Madrid, IdiPAZ Institute for Health Research, Madrid, Spain.
Raquel Gutiérrez-ZúñigaDepartment of Neurology and Stroke Center, La Paz University Hospital, Department of Medicine, Neurosciences Unit, Universidad Autónoma de Madrid, IdiPAZ Institute for Health Research, Madrid, Spain.
José López-TàpperoSpeech and Language Unit, Department of Rehabilitation, La Paz University Hospital and Universidad Complutense de Madrid, Madrid, Spain.
Marta Martín AlonsoSpeech and Language Unit, Department of Rehabilitation, La Paz University Hospital, Madrid, Spain.
Sylvia Pastor-YborraDepartment of Neurology and Stroke Center, La Paz University Hospital, Department of Medicine, Neurosciences Unit, Universidad Autónoma de Madrid, IdiPAZ Institute for Health Research, Madrid, Spain.
Ricardo RigualDepartment of Neurology and Stroke Center, La Paz University Hospital, Department of Medicine, Neurosciences Unit, Universidad Autónoma de Madrid, IdiPAZ Institute for Health Research, Madrid, Spain.
Gerardo Ruiz-AresDepartment of Neurology and Stroke Center, La Paz University Hospital, Department of Medicine, Neurosciences Unit, Universidad Autónoma de Madrid, IdiPAZ Institute for Health Research, Madrid, Spain.
Jorge Rodríguez-PardoDepartment of Neurology and Stroke Center, La Paz University Hospital, Department of Medicine, Neurosciences Unit, Universidad Autónoma de Madrid, IdiPAZ Institute for Health Research, Madrid, Spain.
Javier Virués-OrtegaDepartment of Psychology, Universidad Autónoma de Madrid, Madrid, Spain.
Alberto M BorobiaClinical Trials Unit, Department of Clinical Pharmacology, La Paz University Hospital, IdiPAZ Institute for Health Research, Madrid, Spain.
Paloma BlancoAsociación Afasia Activa, Madrid, Spain.
Nereida Bueno-Guerra *Department of Psychology, Universidad Pontificia Comillas, Madrid, Spain. nbguerra@comillas.edu.
Hospital La Paz Institute for Health Research · ESUniversidad Autónoma de Madrid · ESBarcelona Activa · ESComillas Pontifical University · ESHospital Universitario La Paz · ESUniversidad Complutense de Madrid · ESUniversity of Auckland · NZ

Funding

"la Caixa" Foundation HR18-00026
6 · The paper itself

Abstract

backgroundCommunication is one of the most important predictors of social reintegration after stroke. Approximately 15-42% of stroke survivors experience post-stroke aphasia. Helping people recover from aphasia is one of the research priorities after a stroke. Our aim is to develop and validate a new therapy integrating dubbing techniques to improve functional communication.

methodsThe research project is structured as three work packages (WP). WP1: development of the dubbed language cinema-based therapy: Two research assistants (a speech therapist and a dubbing actor) will select the clips, mute specific words/sentences in progressive speech difficulty, and guide patients to dub them across sessions. Words to be dubbed will be those considered to be functionally meaningful by a representative sample of aphasic patients and relatives through an online survey. WP2: a randomized, crossover, interventional pilot study with the inclusion of 54 patients with post-stroke non-fluent aphasia. Patients will be treated individually in 40-min sessions twice per week for 8 weeks. Primary outcomes will be significant pre/post differences in scores in the Communicative Activity Log (CAL) questionnaire and Boston Diagnostic Aphasia Examination (BDAE) administered by a psychologist blinded to the patients' clinical characteristics. SECONDARY OUTCOMES: General Health Questionnaire (GHQ)-12, Stroke Aphasia Quality of Life Scale (SAQOL-39), Western Aphasia Battery Revised (WAB-R), and the Stroke Aphasic Depression Questionnaire (SADQ10). WP3: educational activities and dissemination of results. WP3 includes educational activities to improve public knowledge of aphasia and dissemination of the results, with the participation of the Spanish patients' association Afasia Activa. DISCUSSION: This pilot clinical trial will explore the efficacy of a new therapeutic tool based on dubbing techniques and computer technology to improve functional communication of patients suffering from post-stroke aphasia with the use of standardized test assessment.

trial registrationClinicalTrials.gov NCT04289493 . Registered on 28 February 2020.

Indexed as

AphasiaStroke RehabilitationHumansLanguageMotion PicturesPilot ProjectsQuality of LifeRandomized Controlled Trials as TopicSpeech TherapyAphasiaProtocolRandomized clinical trialStroke

Identifiers

PMID34991688
PMCPMC8734327
OpenAlexW4206757081

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.