Evidence map›Paper›PMID 34991548›Full record

ArticleBMC public health2022

Exploring barriers and facilitators to PrEP use among transgender women in two urban areas: implications for messaging and communication.

Sarah Bauerle Bass, Patrick J Kelly, Jesse Brajuha, Luis Gutierrez-Mock, Kimberly Koester, Paul D'Avanzo, Jae Sevelius

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  9. Integrating CBPR and Implementation Science to Develop a PrEP-Promotion Intervention for Black Transgender Women.Health education & behavior : the official publication of the Society for Public Health Education · 2026
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  13. Pre-Exposure Prophylaxis Use Among Cisgender and Transgender Adult Entertainment Workers in Brazil.International journal of environmental research and public health · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sarah Bauerle BassDepartment of Social and Behavioral Sciences, Risk Communication Laboratory, Temple University College of Public Health, Temple University College of Public Health, Risk Communication Laboratory, 1301 Cecil B. Moore Ave., Room 945, Philadelphia, PA, 951, USA. sbass@temple.edu.ORCID 0000-0003-2742-1609
Patrick J KellyDepartment of Social and Behavioral Sciences, Risk Communication Laboratory, Temple University College of Public Health, Temple University College of Public Health, Risk Communication Laboratory, 1301 Cecil B. Moore Ave., Room 945, Philadelphia, PA, 951, USA.
Jesse BrajuhaDepartment of Social and Behavioral Sciences, Risk Communication Laboratory, Temple University College of Public Health, Temple University College of Public Health, Risk Communication Laboratory, 1301 Cecil B. Moore Ave., Room 945, Philadelphia, PA, 951, USA.
Luis Gutierrez-MockCenter of Excellence for Transgender Health, University of California San Francisco, San Francisco, CA, USA.
Kimberly KoesterCenter of Excellence for Transgender Health, University of California San Francisco, San Francisco, CA, USA.
Paul D'AvanzoDepartment of Social and Behavioral Sciences, Risk Communication Laboratory, Temple University College of Public Health, Temple University College of Public Health, Risk Communication Laboratory, 1301 Cecil B. Moore Ave., Room 945, Philadelphia, PA, 951, USA.
Jae SeveliusCenter of Excellence for Transgender Health, University of California San Francisco, San Francisco, CA, USA.
Temple University · USUniversity of California, San Francisco · USTemple College · US

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
Mentoring clinical investigators in patient-oriented research on substance use and HIVK24DA051328 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEVELIUS, JAE M. · 2020 to 2024
$771k
Mapping perceptions of PrEP use in transwomen and barriers to care in providers to inform intervention developmentR21MH110340 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI BASS, SARAH B, SEVELIUS, JAE M. · 2017 to 2018
$446k
NIDA NIH HHS K24 DA051328NIMH NIH HHS 1 R21 NG110340-01A1
6 · The paper itself

Abstract

backgroundTrans women are at increased risk for HIV infection yet are less likely to use pre-exposure prophylaxis (PrEP) medication as a preventive measure. PrEP messaging and marketing has focused on men who have sex with men (MSM) or included trans women as a subset of MSM, ignoring the potential barriers to PrEP use unique to trans women. Little is known about how this group conceptualizes PrEP, what knowledge gaps still exist, and how trans women believe PrEP should be communicated to increase use.

methodsThis qualitative study conducted focus groups (n = 5) in Philadelphia and Sacramento with trans women to assess these issues.

resultsTwelve sub-themes were found related to five main domains, including PrEP knowledge, benefits, barriers, community-related considerations, and messaging/marketing. Findings indicate that knowledge of PrEP is still low and beliefs about PrEP's effects on hormone use persist. Most importantly, participants voiced a demand for culturally appropriate trans-specific messages in HIV prevention interventions and communication.

conclusionsWithout acknowledging specific barriers to PrEP uptake among transgender women separate from those of MSM and incorporating gender affirmation into PrEP education, simply knowing PrEP is available may not motivate trans women to use PrEP. This has important implications for future efforts to communicate about PrEP with trans women.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesTransgender PersonsCommunicationFemaleHomosexuality, MaleHumansMaleAnti-HIV AgentsCommunicationFocus groupHIV preventionPrEPTransgender women

Identifiers

PMID34991548
PMCPMC8740429
OpenAlexW4206838594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.