Evidence map›Paper›PMID 34991513›Full record

ArticleBMC pediatrics2022

Cue-based feeding and short-term health outcomes of premature infants in newborn intensive care units: a non-randomized trial.

Sefatbaqa Samane, Zahed Pasha Yadollah, Hasanpour Marzieh, Hajian- Tilaki Karimollah, Zarkesh Mohammad Reza, Arzani Afsaneh, Heidelise Als

Registry-linked trialOpen access · goldAbstract readControlled Clinical Trial
In one paragraph

Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07136610 (Standardized Application of Feeding Evaluations Using SMART Tool), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07136610 narecruitingnot on this mapstarted 2025, after this paper: background citation

Standardized Application of Feeding Evaluations Using SMART Tool

TypeinterventionalSponsorWake Forest University Health SciencesRan2025 to 2027Enrolled3,500ConditionsInfant and Young Child FeedingArmsSMART Tool
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Feeding and swallowing difficulties in previously hospitalised premature infants in the neonatal intensive care unit: Perspectives from South African caregivers.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Sefatbaqa SamaneMaster of Newborn Intensive Care Nursing, School of Nursing and Midwifery, Student Research Committee, Babol University of Medical Sciences, Babol, Iran.
Zahed Pasha YadollahNon-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Hasanpour MarziehPediatric and Neonatal Intensive Care Nursing Education Department, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
Hajian- Tilaki KarimollahDepartment of Biostatistics and Epidemiology, School of Public Health, Babol University of Medical Sciences, Babol, Iran.
Zarkesh Mohammad RezaDepartment of Neonatology, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Arzani AfsanehCenter for Non-Communicable Pediatric Diseases, Health Research Institute, School of Nursing and Midwifery, Babol University of Medical Sciences, Babol, Iran. arzaniaf@gmail.com.
Heidelise AlsDepartment of Psychiatry, Harvard Medical School, Neurobehavioral Infant and Child Studies, Boston Children's Hospital, Boston, MA, USA.
Babol University of Medical Sciences · IRHarvard University · USIranshahr University · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFeedings based on behavioral cues is a method relying on infants' behavioral expressions of readiness to feed. The objective of this interventional study was to determine the effect of cue-based feeding on the short-term health outcomes of preterm infants.

methodsThis quasi-experimental study utilized a historical or phase lag design. It involved 60 preterm infants admitted to an Iranian referral hospital's Level III-Newborn Intensive Care Unit (NICU) from April 2017 until January 2018. The experimental group (n = 30) received a three-step intervention of offering behavioral-cue-based oral (BCBO) feedings: Step 1 - One BCBO feeding every 12 hours for 3 days; Step 2 - Two BCBO feedings every 12 h for 3 days; and Step 3 - All feedings as BCBO feedings for 3 days. The control group received standard care feedings. Group difference data were analyzed with SPSS version 16 using descriptive and inferential statistics.

resultsThe infants' mean weight at time of discharge for the intervention and control groups were 1492.79 ± 21.65 g and 1395.71 ± 17.61 g (P = .003) respectively. The mean durations of achieving full oral feedings in the intervention and control groups were 17 ± 6 and 20 ± 11 days, respectively (P = .19). The mean frequencies of hypoxia were 1 ± 1.54 and 5 ± 9.31 respectively (P = .03) and of gavage feedings 725 ± 584 and 1846 ± 2097 respectively (P = .009). No apnea events were reported for the intervention group; the frequency of apnea in the control group was 1 ± 2.11 (P = .16).

conclusionThe findings indicate that cue-based feeding is beneficial for preterm infants. Therefore, it is recommended that nurses employ cue-based feeding in the NICU.

trial registrationIRCTID: IRCT20170828035962N2. Registered 27 may 2018 - Retrospectively registered, https://en.irct.ir/trial/27024 .

Indexed as

CuesIntensive Care Units, NeonatalHumansInfantInfant, NewbornInfant, PrematureIranOutcome Assessment, Health CareCuesFeeding methodsHealth careInfantNursesOutcome assessmentPremature

Identifiers

PMID34991513
PMCPMC8734045
OpenAlexW4206428211

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.