Evidence map›Paper›PMID 34991158›Full record

ArticleBlood advances2022

G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL.

Ilaria Iacobucci, Reiji Fukano, Jake D Friske, Chunxu Qu, Laura J Janke, Yaqi Zhao, Pradyuamna Baviskar, Emily A Backhaus, Peter Chockley, Aman Seth and 3 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Ilaria IacobucciDepartment of Pathology, and.ORCID 0000-0003-2008-1365
Reiji FukanoDepartment of Pathology, and.ORCID 0000-0002-4087-3426
Jake D FriskeDepartment of Pathology, and.ORCID 0000-0001-8987-8538
Chunxu QuDepartment of Pathology, and.
Laura J JankeDepartment of Pathology, and.
Yaqi ZhaoDepartment of Pathology, and.ORCID 0000-0002-8230-5312
Pradyuamna BaviskarDepartment of Pathology, and.
Emily A BackhausDepartment of Pathology, and.ORCID 0000-0002-1253-9148
Peter ChockleyDepartment of Bone Marrow Transplantation and Cell Therapy, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-5181-2696
Aman SethDepartment of Pathology, and.
A Douglas LairdPfizer, Inc., La Jolla, CA.
Anjali S AdvaniCleveland Clinic, Cleveland, OH; and.ORCID 0000-0003-0015-5902
Charles G MullighanDepartment of Pathology, and.ORCID 0000-0002-1871-1850
St. Jude Children's Research Hospital · USCleveland Clinic · USPfizer (United States) · USYamaguchi University · JP

Funding

Translating genomic discoveries to improved outcomes for high risk acute leukemiaR35CA197695 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Charles G Mullighan · 2017 to 2026
$11.4M
NCI NIH HHS R35 CA197695
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LeukemiaAdaptor Proteins, Signal TransducingCarrier ProteinsHumansRNA-Binding ProteinsAdaptor Proteins, Signal TransducingCarrier ProteinsG3BP2 protein, humanRNA-Binding Proteins

Identifiers

PMID34991158
PMCPMC9198944
OpenAlexW4205928971

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.