ArticleObstetrics and gynecology2022
Pregnancy-Associated Deaths Due to Drugs, Suicide, and Homicide in the United States, 2010-2019.
Article in Obstetrics and gynecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.
- Synthesizing Cohort Study Results to Promote Knowledge Transfer of Safety Data Regarding Gestational Antidepressant Exposure and Offspring Congenital Anomalies: A Test of Concept.Birth defects research · 2025Pooled it
- Factors Associated With Opioid-Involved Overdose: Descriptive Data From a Randomized Controlled Trial Evaluating Extended-Release Buprenorphine for Perinatal Opioid Use Disorder.Substance use & addiction journal · 2026Trial
- Duration of Medication Use for Opioid Use Disorder and Risk of Postpartum Overdose and Death.JAMA network open · 2026Article
- Pregnancy, Postpartum, and Parenting Engagement Resource Center: A national resource for researchers, community organizations, and parents with substance use disorders.Drug and alcohol dependence reports · 2026Article
- Perinatal mental health screening and care among those with pregnancy complications.American journal of obstetrics & gynecology MFM · 2026Review
- Nursing Students' Knowledge, Attitudes, and Skills Related to Perinatal Substance Use.Substance use & addiction journal · 2026Article
- Opioid use disorder and medication for opioid use disorder among pregnant women with commercial insurance in the United States, 2016-2020.Drug and alcohol dependence · 2026Article
- Abortion Bans and Maternal, Pregnancy-Related, and Pregnancy-Associated Mortality in 14 US States, 2016-2023: Estimated Impacts Amid Substantial Measurement Challenges.American journal of public health · 2026Article
- Utility of Methadone:Metabolite Ratio as Marker of Methadone Metabolism During Methadone Initiation in Pregnancy.Journal of addiction medicine · 2026Article
- Referral linkages to support pregnant and postpartum individuals with opioid use disorders in Florida: a social network analysis.Addiction science & clinical practice · 2026Article
- Experiences of pregnant and postpartum people of color engaged in a randomized clinical trial of medication to treat opioid use disorder during pregnancy: A "Positive Outliers" analysis.Journal of substance use and addiction treatment · 2026Article
- Association Between Mental Illness and Risk of Severe Maternal Morbidity in Pregnant Veterans.Obstetrics and gynecology · 2026Article
- Therapeutic Update in Neonatal Opioid Withdrawal Syndrome: Comparative Effectiveness of Pharmacological Treatments and the ESC Assessment Model. A Systematic Review.Health science reports · 2026Review
- Screening Using the Edinburgh Postnatal Depression Scale at Delivery Discharge as a Predictor of Postpartum Depression.International journal of behavioral medicine · 2026Article
- Using human-centered design to map the perinatal ecosystem for pregnant people with substance use disorders.Pregnancy (Hoboken, N.J.) · 2026Article
- Acceptability and use of the Saving Mothers mPOWHER Maternal Health Kit.Journal of racial and ethnic health disparities · 2026Article
- Infant Caregiving as a Resilience Factor for Postpartum Substance Misuse: A Scoping Review.Adversity and resilience science · 2026Review
- Cohort profile: Mothers who use substances and their children in British Columbia, Canada.PloS one · 2026Article
- Site-randomised trial of a multilevel digital intervention to reduce maternal morbidity and mortality: a study protocol.BMJ open · 2025Article
- Impact of substance use and trauma on postpartum readmission rates and hospitalization costs: An observational study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Observational
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo estimate the prevalence of pregnancy-associated deaths due to drugs, suicide, and homicide nationwide from 2010 to 2019.
methodsUsing U.S. death certificate records from 2010 to 2019 for 33 states plus the District of Columbia, we identified pregnancy-associated deaths using the pregnancy checkbox and International Classification of Diseases, Tenth Revision codes, calculated pregnancy-associated death ratios, and categorized deaths by cause, timing relative to pregnancy, race or ethnicity, and age.
resultsOf 11,782 pregnancy-associated deaths identified between 2010 and 2019, 11.4% were due to drugs, 5.4% were due to suicide, and 5.4% were due to homicide, whereas 59.3% were due to obstetric causes and the remaining 18.5% were due to other causes. Drug-related deaths, suicide, and homicide accounted for 22.2% of pregnancy-associated deaths. All three causes of death increased over the study period, with drug-related pregnancy-associated deaths increasing 190%. Homicide during pregnancy and drug-related deaths, suicides, and homicide in the late postpartum period (43-365 days) accounted for a larger proportion of all deaths in these time periods than the contribution of these causes to all deaths among females of reproductive age. Pregnant and postpartum people identified as non-Hispanic American Indian or Alaska Native were at highest risk of drug-related and suicide death, and people identified as non-Hispanic Black were at highest risk of homicide.
conclusionDeaths due to drug use, suicide, and homicide constitute more than one fifth of all deaths during pregnancy and the first year postpartum. Drug-related deaths and homicides have increased over the past decade. Substantial racial and ethnic inequities in these deaths exist.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.