Evidence map›Paper›PMID 34990686›Full record

ArticleThe Science of the total environment2022

Interactive effects of cold spell and air pollution on outpatient visits for anxiety in three subtropical Chinese cities.

Huan Li, Min Li, Shiyu Zhang, Zhengmin Min Qian, Zilong Zhang, Kai Zhang, Chongjian Wang, Lauren D Arnold, Stephen Edward McMillin, Shaowei Wu and 2 more

Abstract read
In one paragraph

Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Combined effects of apparent low temperature and PMFrontiers in public health · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Synergic effects of PMJournal of exposure science & environmental epidemiology · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Huan LiDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Min LiDepartment of Preventive Medicine, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, The Third Clinical Medical Institute Affiliated to Guangzhou University of Chinese Medicine, Guangzhou, China.
Shiyu ZhangDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Zhengmin Min QianDepartment of Epidemiology and Biostatistics, College for Public Health & Social Justice, Saint Louis University, Saint Louis, USA.
Zilong ZhangDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Kai ZhangDepartment of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, USA.
Chongjian WangDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, China.
Lauren D ArnoldDepartment of Epidemiology and Biostatistics, College for Public Health & Social Justice, Saint Louis University, Saint Louis, USA.
Stephen Edward McMillinSchool of Social Work, College for Public Health & Social Justice, Saint Louis University, Saint Louis, USA.
Shaowei WuDepartment of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710000, China.
Fei TianDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Hualiang LinDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. Electronic address: linhualiang@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough low temperature and air pollution exposures have been associated with the risk of anxiety, their combined effects remain unclear.

objectiveTo investigate the independent and interactive effects of low temperature and air pollution exposures on anxiety.

methodUsing a case-crossover study design, the authors collected data from 101,636 outpatient visits due to anxiety in three subtropical Chinese cities during the cold season (November to April in 2013 through 2018), and then built conditional logistic regression models based on individual exposure assessments [temperature, relative humidity, particulate matter (PM

resultsBoth cold spell and air pollution were significantly associated with outpatients for anxiety. The effects of cold spell increased with its intensity, ranging from 8.98% (95% CI: 2.02%, 16.41%) to 15.24% (95% CI: 6.75%, 24.39%) in Huizhou. Additionally, each 10 μg/m

conclusionsThese findings indicate that both cold spell and air pollution are important drivers of the occurrence of anxiety, and simultaneous exposure to these two factors might have synergistic effects on anxiety. These findings highlight the importance of controlling air pollution and improving cold-warning systems.

Indexed as

Air PollutantsAir PollutionAdolescentAdultAgedAnxietyChinaCitiesCross-Over StudiesHumansMiddle AgedNitrogen DioxideOutpatientsParticulate MatterYoung AdultAir PollutantsNitrogen DioxideParticulate MatterAir pollutionAnxietyCold spell

Identifiers

PMID34990686
PMCPMC8907861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.