ArticleEpidemiology and health2022
An outbreak of hepatitis A associated with salted clams in Busan, Korea.
Article in Epidemiology and health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Hepatitis A serostatus and vaccination outcomes after on-campus education and point-of-care antibody testing.Frontiers in public health · 2026Article
- Gender differences in hepatitis A seropositivity rates according to the Republic of Korea's vaccination policy.Osong public health and research perspectives · 2024Article
- Investigating the spatio-temporal variation of hepatitis A in Korea using a Bayesian model.Frontiers in public health · 2022Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesIn July 2019, there were multiple reports on patients with hepatitis A among the visitors of a restaurant in Busan. The current study presents the results of an epidemiological investigation and outlines the supplementary measures that would help with hepatitis A control.
methodsA cohort study was conducted for all 2,865 customers who visited restaurant A from June to July. Using a standardized questionnaire, participants reported the presence of hepatitis A symptoms and whether they had consumed any of 19 food items. As for participants who had visited public health centers, their specimens were collected.
resultsFrom the study cohort, 155 participants (5.4%) had confirmed hepatitis A. The epidemic curve was unimodal, and the median number of days from the restaurant visit to symptom onset was 31 days. A genotype analysis indicated that 89 of 90 tested patients had hepatitis A virus (HAV) genotype 1A. The results of a multivariate logistic regression analysis indicated that the ingestion of salted clams increased the risk of hepatitis A by 68.12 times (95% confidence interval [CI], 9.22 to 510.87). In an unopened package of salted clams found and secured through traceback investigation, HAV genotype 1A was detected.
conclusionsTo prevent people from ingesting uncooked clams, there needs to be more efforts to publicize the dangers of uncooked clams; the food sampling test standards for salted clams should also be expanded. Furthermore, a laboratory surveillance system based on molecular genetics should be established to detect outbreaks earlier.
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