Evidence map›Paper›PMID 34990489›Full record

ArticlePloS one2022

Pandemic-related declines in hospitalization for non-COVID-19-related illness in the United States from January through July 2020.

Jennifer L Nguyen, Michael Benigno, Deepa Malhotra, Farid Khan, Frederick J Angulo, Jennifer Hammond, David L Swerdlow, Maya Reimbaeva, Birol Emir, John M McLaughlin

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 38 citations in OpenAlex.

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  17. Frailty Trends in an Older Veteran Subpopulation 1 Year Prior and Into the COVID-19 Pandemic Using CAN Scores.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jennifer L NguyenReal World Evidence Center of Excellence, Pfizer Inc, New York, NY, United States of America.ORCID 0000-0002-4064-0227
Michael BenignoReal World Evidence Center of Excellence, Pfizer Inc, New York, NY, United States of America.
Deepa MalhotraReal World Evidence Center of Excellence, Pfizer Inc, New York, NY, United States of America.
Farid KhanMedical Development and Scientific/Clinical Affairs, Pfizer Vaccines, Pfizer Inc, Collegeville, PA, United States of America.
Frederick J AnguloMedical Development and Scientific/Clinical Affairs, Pfizer Vaccines, Pfizer Inc, Collegeville, PA, United States of America.
Jennifer HammondClinical Development Internal Medicine and Hospital, Pfizer Global Product Development, Pfizer Inc, Collegeville, PA, United States of America.
David L SwerdlowMedical Development and Scientific/Clinical Affairs, Pfizer Vaccines, Pfizer Inc, Collegeville, PA, United States of America.
Maya ReimbaevaGlobal Biometrics and Data Management, Pfizer Global Product Development, Pfizer Inc, Groton, CT, United States of America.
Birol EmirGlobal Biometrics and Data Management, Pfizer Global Product Development, Pfizer Inc, New York, NY, United States of America.
John M McLaughlinMedical Development and Scientific/Clinical Affairs, Pfizer Vaccines, Pfizer Inc, Collegeville, PA, United States of America.
Pfizer (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic, caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has substantially impacted healthcare utilization worldwide. The objective of this retrospective analysis of a large hospital discharge database was to compare all-cause and cause-specific hospitalizations during the first six months of the pandemic in the United States with the same months in the previous four years.

methodsData were collected from all hospitals in the Premier Healthcare Database (PHD) and PHD Special Release reporting hospitalizations from January through July for each year from 2016 through 2020. Hospitalization trends were analyzed stratified by age group, major diagnostic categories (MDCs), and geographic region.

resultsThe analysis included 286 hospitals from all 9 US Census divisions. The number of all-cause hospitalizations per month was relatively stable from 2016 through 2019 and then fell by 21% (57,281 fewer hospitalizations) between March and April 2020, particularly in hospitalizations for non-respiratory illnesses. From April onward there was a rise in the number of monthly hospitalizations per month. Hospitalizations per month, nationally and in each Census division, decreased for 20 of 25 MDCs between March and April 2020. There was also a decrease in hospitalizations per month for all age groups between March and April 2020 with the greatest decreases in hospitalizations observed for patients 50-64 and ≥65 years of age.

conclusionsRates of hospitalization declined substantially during the first months of the COVID-19 pandemic, suggesting delayed routine, elective, and emergency care in the United States. These lapses in care for illnesses not related to COVID-19 may lead to increases in morbidity and mortality for other conditions. Thus, in the current stage of the pandemic, clinicians and public-health officials should work, not only to prevent SARS-CoV-2 transmission, but also to ensure that care for non-COVID-19 conditions is not delayed.

Indexed as

COVID-19Delivery of Health CareHospitalizationHospitalsHumansPandemicsPatient Acceptance of Health CareRetrospective StudiesSARS-CoV-2United States

Identifiers

PMID34990489
PMCPMC8735608
OpenAlexW4206510521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.