Evidence map›Paper›PMID 34990485›Full record

ArticlePloS one2022

Unstructured clinical notes within the 24 hours since admission predict short, mid & long-term mortality in adult ICU patients.

Maria Mahbub, Sudarshan Srinivasan, Ioana Danciu, Alina Peluso, Edmon Begoli, Suzanne Tamang, Gregory D Peterson

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  6. Analyzing Information Disparities across Modalities in Mortality Prediction.medRxiv : the preprint server for health sciences · 2025
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  10. Review
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  15. A comparative study of pretrained language models for long clinical text.Journal of the American Medical Informatics Association : JAMIA · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria MahbubCyber Resilience and Intelligence Division, Oak Ridge National Laboratory, Oak Ridge, TN, United States of America.ORCID 0000-0002-3422-9650
Sudarshan SrinivasanCyber Resilience and Intelligence Division, Oak Ridge National Laboratory, Oak Ridge, TN, United States of America.
Ioana DanciuComputational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN, United States of America.
Alina PelusoComputational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN, United States of America.
Edmon BegoliCyber Resilience and Intelligence Division, Oak Ridge National Laboratory, Oak Ridge, TN, United States of America.
Suzanne TamangCenter for Population Health Science, Stanford University, Palo Alto, CA, United States of America.
Gregory D PetersonDepartment of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mortality prediction for intensive care unit (ICU) patients is crucial for improving outcomes and efficient utilization of resources. Accessibility of electronic health records (EHR) has enabled data-driven predictive modeling using machine learning. However, very few studies rely solely on unstructured clinical notes from the EHR for mortality prediction. In this work, we propose a framework to predict short, mid, and long-term mortality in adult ICU patients using unstructured clinical notes from the MIMIC III database, natural language processing (NLP), and machine learning (ML) models. Depending on the statistical description of the patients' length of stay, we define the short-term as 48-hour and 4-day period, the mid-term as 7-day and 10-day period, and the long-term as 15-day and 30-day period after admission. We found that by only using clinical notes within the 24 hours of admission, our framework can achieve a high area under the receiver operating characteristics (AU-ROC) score for short, mid and long-term mortality prediction tasks. The test AU-ROC scores are 0.87, 0.83, 0.83, 0.82, 0.82, and 0.82 for 48-hour, 4-day, 7-day, 10-day, 15-day, and 30-day period mortality prediction, respectively. We also provide a comparative study among three types of feature extraction techniques from NLP: frequency-based technique, fixed embedding-based technique, and dynamic embedding-based technique. Lastly, we provide an interpretation of the NLP-based predictive models using feature-importance scores.

Indexed as

Hospital MortalityMachine LearningArea Under CurveDatabases, FactualElectronic Health RecordsHumansIntensive Care UnitsLength of StayLogistic ModelsROC Curve

Identifiers

PMID34990485
PMCPMC8735614

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.