Evidence map›Paper›PMID 34990293›Full record

ArticleJCO oncology practice2022

Exercise Recommendation for People With Bone Metastases: Expert Consensus for Health Care Providers and Exercise Professionals.

Kristin L Campbell, Prue Cormie, Sarah Weller, Shabbir M H Alibhai, Kate A Bolam, Anna Campbell, Andrea L Cheville, Mary-Ann Dalzell, Nicolas H Hart, Celestia S Higano and 12 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
23.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.

  1. Effect of exercise on bone-related outcomes in patients with cancer affected by bone metastases or bone loss: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  2. Trial
  3. Trial
  4. Prehabilitation to improve function after autologous stem cell transplantation: A pilot randomized controlled trial (PIRATE).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  5. Trial
  6. ExPeCT: a randomised trial examining the impact of exercise on quality of life in men with metastatic prostate cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  7. Review
  8. Practical recommendations for exercise and nutrition in patients with lung cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  9. Observational
  10. Exercise for myeloma patients with bone disease: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Management of bone health in cancer survivorship: a systematic review of clinical guidelines.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
  15. Article
  16. Review
  17. Article
  18. The Bone Metastases and Exercise (BME) Hub: a MASCC-endorsed knowledge mobilization initiative to advance exercise recommendations for people with bone metastases.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  19. Review
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 15 institutions in 7 countries.

Kristin L CampbellDepartment of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-2266-1382
Prue CormieAustralian Catholic University, Melbourne, Australia.ORCID 0000-0002-3446-2698
Sarah WellerDepartment of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada.
Shabbir M H AlibhaiToronto General Hospital and University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-7815-6046
Kate A BolamKarolinska Institute, Stockholm, Sweden.
Anna CampbellEdinburgh Napier University, Edinburgh, Scotland.ORCID 0000-0003-3517-7335
Andrea L ChevilleMayo Clinic, Rochester, NY.ORCID 0000-0001-7668-6115
Mary-Ann DalzellOncology Division of the Canadian Physiotherapy Association, Montreal, Quebec, Canada.
Nicolas H HartEdith Cowan University, Joondalup, Australia.ORCID 0000-0003-2794-0193
Celestia S HiganoVancouver Prostate Centre, Vancouver, British Columbia, Canada.ORCID 0000-0001-5308-8972
Kirstin LaneUniversity of Victoria, Victoria, British Columbia, Canada.ORCID 0000-0002-3786-8191
Sami MansfieldUniversity of Kansas Cancer Center, Kansas City, MO.
Margaret L McNeelyUniversity of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0003-4376-4847
Robert U NewtonEdith Cowan University, Joondalup, Australia.ORCID 0000-0003-0302-6129
Morten QuistUniversity of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-0983-957X
Jennifer RauwBC Cancer, Vancouver, British Columbia, Canada.
Friederike RosenbergerNational Center for Tumor Diseases, Heidelberg, Germany.ORCID 0000-0002-4147-2958
Daniel Santa MinaUniversity of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-4361-1656
Kathryn H SchmitzPenn State University, Hershey, PA.ORCID 0000-0003-2400-2935
Kerri M Winters-StoneOregon Health and Sciences University, Portland, OR.
Joachim WiskemannNational Center for Tumor Diseases, Heidelberg, Germany.ORCID 0000-0002-5971-5436
Jennifer GoulartBC Cancer, Victoria, British Columbia, Canada.ORCID 0000-0003-1533-1489
Edith Cowan University · AUNational Center for Tumor Diseases · DEUniversity of British Columbia · CAUniversity of Toronto · CACanadian Physiotherapy Association · CAEdinburgh Napier University · GBKarolinska Institutet · SEMayo Clinic · USOregon Health & Science University · USPenn State Milton S. Hershey Medical Center · USPeter MacCallum Cancer Centre · AUThe University of Kansas Cancer Center · USUniversity of Alberta · CAUniversity of Copenhagen · DKUniversity of Victoria · CA

Funding

Understanding the origins of rapid recurrence of pancreatic cancer after resectionP30CA069533 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Grace B Gill · 1997 to 2026
$60.5M
Preventing Falls and Frailty in Prostate Cancer Survivors: GET FIT ProstateR01CA222605 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI WINTERS-STONE, KERRI M · 2018 to 2022
$3.3M
Exploring the concept of dyadic health in Thai couples coping with breast cancer: A preliminary study of a partnered approach to physical activity in breast cancer survivors and spouse care partnersR01CA218093 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI WINTERS-STONE, KERRI M · 2018 to 2022
$3.3M
NCI NIH HHS P30 CA069533NCI NIH HHS R01 CA218093NCI NIH HHS R01 CA222605
6 · The paper itself

Abstract

purposeExercise has been underutilized in people with advanced or incurable cancer despite the potential to improve physical function and reduce psychosocial morbidity, especially for people with bone metastases because of concerns over skeletal complications. The International Bone Metastases Exercise Working Group (IBMEWG) was formed to develop best practice recommendations for exercise programming for people with bone metastases on the basis of published research, clinical experience, and expert opinion.

methodsThe IBMEWG undertook sequential steps to inform the recommendations: (1)

resultsRecommendations emerged from the contributing evidence and IBMEWG discussion for pre-exercise screening, exercise testing, exercise prescription, and monitoring of exercise response. Identification of individuals who are potentially at higher risk of exercise-related skeletal complication is a complex interplay of these factors: (1) lesion-related, (2) cancer and cancer treatment-related, and (3) the person-related. Exercise assessment and prescription requires consideration of the location and presentation of bone lesion(s) and should be delivered by qualified exercise professionals with oncology education and exercise prescription experience. Emphasis on postural alignment, controlled movement, and proper technique is essential.

conclusionUltimately, the perceived risk of skeletal complications should be weighed against potential health benefits on the basis of consultation between the person, health care team, and exercise professionals. These recommendations provide an initial framework to improve the integration of exercise programming into clinical care for people with bone metastases.

Indexed as

ExerciseNeoplasmsConsensusCross-Sectional StudiesExercise TherapyHealth PersonnelHumans

Identifiers

PMID34990293
PMCPMC9810134
OpenAlexW4205167728

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.