Evidence map›Paper›PMID 34990108›Full record

ReviewChemical research in toxicology2022

Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration.

Tauqeerunnisa Syeda, Jason R Cannon

Open access · greenAbstract readReview
In one paragraph

Review in Chemical research in toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Dual-pathway detoxification byFood chemistry: X · 2026
    Article
  4. Neuromelanin-induced cellular stress and neurotoxicity in the pathogenesis of Parkinson's disease.Apoptosis : an international journal on programmed cell death · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tauqeerunnisa SyedaSchool of Health Sciences, Purdue University, West Lafayette, Indiana 47907, United States.
Jason R CannonSchool of Health Sciences, Purdue University, West Lafayette, Indiana 47907, United States.ORCID 0000-0003-1907-4555
Purdue University West Lafayette · US

Funding

Mechanisms of PhIP-induced dopaminergic neurotoxicityR01ES025750 · NIEHS · PURDUE UNIVERSITY · PI Jason R Cannon · 2016 to 2026
$4.2M
NIEHS NIH HHS R01 ES025750
6 · The paper itself

Abstract

Heterocyclic aromatic amines (HAAs) are mainly formed in the pyrolysis process during high-temperature cooking of meat. Meat consumption is very typical of the western diet, and the amount of meat consumption in the eastern countries is growing rapidly; HAAs represents widespread exposure. HAAs are classified as possible human carcinogens; numerous epidemiological studies have demonstrated regular consumption of meat with HAAs as risk factor for cancers. Specific HAAs have received major attention. For example, 2-amino-1-methyl-6-phenylimidazo[4,5-

Indexed as

AminesAnimalsHeterocyclic CompoundsHumansNeurodegenerative DiseasesAminesHeterocyclic Compounds

Identifiers

PMID34990108
PMCPMC10443083
OpenAlexW4205400177

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.