Evidence map›Paper›PMID 34990004›Full record

ReviewAmerican journal of clinical dermatology2022

Medical Management of Hidradenitis Suppurativa with Non-Biologic Therapy: What's New?

Soha Ghanian, Mika Yamanaka-Takaichi, Haley B Naik, Afsaneh Alavi

Open access · greenAbstract readReview
In one paragraph

Review in American journal of clinical dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Australasian hidradenitis suppurativa management guidelines.The Australasian journal of dermatology · 2025
    Guideline
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Unlocking the Mechanisms of Hidradenitis Suppurativa: Inflammation and miRNA Insights.Clinical, cosmetic and investigational dermatology · 2024
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Soha GhanianDepartment of Dermatology, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Mika Yamanaka-TakaichiDepartment of Dermatology, Mayo Clinic, Rochester, MN, USA.
Haley B NaikDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.
Afsaneh AlaviDepartment of Dermatology, Mayo Clinic, Rochester, MN, USA. alavi.afsaneh@mayo.edu.
Mayo Clinic in Arizona · USBrown University · USUniversity of California, San Francisco · US

Funding

Microbial Shifts and Immune Dysregulation in Hidradenitis Suppurativa PathogenesisK23AR074531 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAIK, HALEY · 2019 to 2023
$887k
NIAMS NIH HHS K23 AR074531
6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a severe chronic relapsing inflammatory disorder of the hair follicle unit that can cause painful abscesses, nodules, tunnels, and tracts in intertriginous parts of the body. The disease can often result in disfigurement and adversely impact patient quality of life. The management of HS has expanded significantly over the past decade to include multiple modalities, including topical therapies, systemic therapies (non-biologics and biologics), surgical therapies, lifestyle changes, and management of comorbidities. Management can often be clinically challenging and may involve the combination of medical and surgical approaches for optimal results. The purpose of this review is to present an update on non-biologic and non-interventional modalities published in 2019-2021 in the clinical management of HS. With emerging therapies, ongoing clinical trials, and heightened awareness about HS, there is hope that new treatment options will revolutionize the management of patients suffering from HS.

Indexed as

Hidradenitis SuppurativaAbscessComorbidityHair FollicleHumansQuality of Life

Identifiers

PMID34990004
PMCPMC9131893
OpenAlexW4206455416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.