ArticleBrain imaging and behavior2022
Investigating the overlapping associations of prior concussion, default mode connectivity, and executive function-based symptoms.
Article in Brain imaging and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Long-term neurobehavioral and neuroimaging outcomes in athletes with prior concussion(s) and head impact exposure.The Clinical neuropsychologist · 2025Review
- Intraindividual variability, subjective cognitive difficulties, and head injury history in former collegiate athletes.The Clinical neuropsychologist · 2025Article
- Linking a Deep Learning Model for Concussion Classification with Reorganization of Large-Scale Brain Networks in Female Youth.Bioengineering (Basel, Switzerland) · 2025Article
- A Comparative Neuroimaging Review of Repetitive Head Impacts and Mild Traumatic Brain Injury from Pediatrics to Professionals.Neurotrauma reports · 2025Review
- Perceptual Response Training for Reduction of Injury Risk Among High School Girls' Soccer Players.Brain sciences · 2024Article
- White Matter Hyperintensities and Microstructural Alterations in Contact Sport Athletes from Adolescence to Early Midlife.Journal of neurotrauma · 2024Article
- Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study.Frontiers in neurology · 2024Article
- Concussion history and virtual reality metrics predict core or lower extremity injury occurrence among high school athletes.Frontiers in sports and active living · 2024Article
- Subtle impairments of perceptual-motor function and well-being are detectable among military cadets and college athletes with self-reported history of concussion.Frontiers in sports and active living · 2023Article
- Observational
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Growing evidence suggests that younger athletes with greater concussion history are more likely to endorse greater subjective cognitive (e.g., executive function) symptoms, but not perform worse on objective cognitive testing. We sought to identify biological correlates of elevated cognitive symptoms in 100 healthy, collegiate-aged athletes with varying degrees of concussion history. Associations between concussion history with subjectively-rated executive function were assessed with generalized linear models. Using resting state fMRI, we examined associations between concussion history and between-and within-network connectivity across three networks integral to executive function; default mode network (DMN), frontoparietal network (FPN), and ventral attention network (VAN). Relationships of between-and within-network connectivity with subjective executive function were assessed. Although the large majority of participants did not report clinically relevant levels of executive difficulties, there was a significant association between concussion history and higher behavioral regulation-related symptoms; B = .04[.01, .07], p = .011. A significant elevation in total within-network connectivity was observed among those with a greater concussion history, B = .02[.002, .03], p = .028, which was primarily driven by a positive association between concussion history and within DMN connectivity, B = .02[.004, .04], p = .014. Higher behavioral regulation-related symptoms were associated with greater total within-network connectivity, B = 0.57[0.18, 0.96], p = .005, and increased within-network connectivity for the DMN, B = .49[.12, .86], p = .010). The current study identified a distinct biological correlate, increased within-DMN connectivity, which was associated with both a greater history of concussion and greater behavioral regulation symptoms. Future studies are required to determine the degree to which these changes associated with concussion history may evolve toward objective cognitive decline over the lifespan.
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