Evidence map›Paper›PMID 34989961›Full record

ReviewMolecular biology reports2022

Long non-coding RNA small nucleolar RNA host genes: functions and mechanisms in hepatocellular carcinoma.

Yuan Li, Xinxin Wang, Shiyong Chen, Biao Wu, Yu He, Xueqin Du, Xiaojun Yang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. The Functions and Mechanisms of Long Non-coding RNA SNHGs in Gastric Cancer.Combinatorial chemistry & high throughput screening · 2024
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuan LiCollege of Clinical Medicine, Ningxia Medical University, Yinchuan, 750000, China.
Xinxin WangDepartment of General Surgery, Gansu Provincial Hospital, Lanzhou, 730000, China.
Shiyong ChenDepartment of General Surgery, Gansu Provincial Hospital, Lanzhou, 730000, China.
Biao WuDepartment of General Surgery, Gansu Provincial Hospital, Lanzhou, 730000, China.
Yu HeDepartment of General Surgery, Gansu Provincial Hospital, Lanzhou, 730000, China.
Xueqin DuDepartment of General Surgery, Gansu Provincial Hospital, Lanzhou, 730000, China.
Xiaojun YangDepartment of General Surgery, Gansu Provincial Hospital, Lanzhou, 730000, China. yangxjmd@aliyun.com.

Funding

Gansu Province innovation base and talent project funding 20JR10RA433Hospital Key Program of National Scientific Research Cultivation Plan 19SYPYA-12National Natural Science Foundation of China 81660398
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors of the digestive system, with a high degree of malignancy. Although treatment methods are constantly improving, the mortality of patients is still very high, and the small nucleolar RNA host gene (SNHG) plays an important role in the occurrence and development of cancer. It can activate downstream signaling molecules by acting on microRNA and microRNA target genes, promote the proliferation, invasion, and migration of HCC cells, and provide a new molecular target for the treatment of HCC. At present, the molecular mechanisms of HCC remain unclear. In this study, the mechanism and signaling pathway of SNHG in HCC are reviewed, which provides a theoretical basis for the clinical treatment of HCC.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMicroRNAsRNA, Long NoncodingCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansRNA, Small NucleolarMicroRNAsRNA, Long NoncodingRNA, Small NucleolarHCCLncRNASignaling pathwaySNHGs

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.