Evidence map›Paper›PMID 34989955›Full record

ArticleInternational ophthalmology2022

Posterior corneal elevation changes and characteristic analysis 1 year after corneal collagen cross-linking for keratoconus.

Jing Li, Shengsheng Wei, Yaohua Zhang, Dan Yang, Zhen Tian, Jing Du, Yong Li, Jianguo Liu, Yan Wang

Abstract read
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Effects of femtosecond laser-assisted minimally invasive lamellar keratoplasty (FL-MILK) on mild-to-moderate and advanced keratoconus.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jing LiClinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.
Shengsheng WeiClinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.
Yaohua ZhangShaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Dan YangShaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Zhen TianShaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Jing DuShaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Yong LiShaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Jianguo LiuShaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Yan WangClinical College of Ophthalmology, Tianjin Medical University, Tianjin, China. wangyan7143@vip.sina.com.ORCID http://orcid.org/0000-0002-1257-6635
Xi'an Jiaotong University · CNTianjin Medical University · CNTianjin Medical University Eye Hospital · CN

Funding

innovative research group project of the national natural science foundation of china 81670884innovative research group project of the national natural science foundation of china 81873684
6 · The paper itself

Abstract

purposeTo investigate the changes in posterior corneal elevations (PCEs) in the circular areas and local points after corneal collagen cross-linking (CXL) for the treatment of keratoconus.

methodsMethod 1 divided the cornea into 0-2, 2-4, 4-6, and 6-8 mm regions centering on the apex. Method 2 obtained other 34 PCE values of local point that were identified on the nasal, supra-nasal, sub-nasal, superior, inferior, temporal, supra-temporal, and sub-temporal sides of the circle with diameters of 2, 4, 6, and 8 mm, and the apex and thinnest point.

resultsMethod 1 showed a forward displacement of PCE at 1 month after CXL and then a backward displacement at 3 months. In Method 2, the points on the temporal side of 2 mm and 4 mm showed the same trend. The backward displacements of PCE on the temporal side of 2 mm at 6 months and on the temporal side of 4 mm at 12 months after CXL were both statistically different than those at 1 month after CXL (P < 0.05). No significant forward displacement of PCE was found in all local points in different quadrants at 1 year after CXL.

conclusionThe PCEs in circular areas and characteristic points of different diameters in keratoconic eyes after CXL change with time. Local point assessment of the PCE is more clinically significant. In points selected in different quadrants of the cornea, the change in temporal points was more significant after CXL.

Indexed as

KeratoconusPhotochemotherapyCollagenCorneaCorneal StromaCorneal TopographyCross-Linking ReagentsHumansPhotosensitizing AgentsRiboflavinUltraviolet RaysCollagenCross-Linking ReagentsPhotosensitizing AgentsRiboflavinCorneaCorneal collagen cross-linkingKeratoconusPosterior corneal elevations

Identifiers

PMID34989955
OpenAlexW4205962322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.