Evidence map›Paper›PMID 34989907›Full record

ArticleAMB Express2022

φYeO3-12 phage tail fiber Gp17 as a promising high specific tool for recognition of Yersinia enterocolitica pathogenic serotype O:3.

Karolina Filik, Bożena Szermer-Olearnik, Joanna Niedziółka-Jönson, Ewa Roźniecka, Jarosław Ciekot, Anna Pyra, Irwin Matyjaszczyk, Mikael Skurnik, Ewa Brzozowska

Open access · goldAbstract read
In one paragraph

Article in AMB Express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
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  6. The NovelViruses · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Karolina FilikHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 R. Weigl St, 53114, Wroclaw, Poland.
Bożena Szermer-OlearnikHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 R. Weigl St, 53114, Wroclaw, Poland.
Joanna Niedziółka-JönsonInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44, 5201-224, Warsaw, Poland.
Ewa RoźnieckaInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44, 5201-224, Warsaw, Poland.
Jarosław CiekotHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 R. Weigl St, 53114, Wroclaw, Poland.
Anna PyraFaculty of Chemistry, University of Wroclaw, 14 F. Joliot-Curie St, 50383, Wroclaw, Poland.
Irwin MatyjaszczykDepartment of Mycology and Genetics, Institute of Genetics and Microbiology, University of Wrocław, 51-148, Wroclaw, Poland.
Mikael SkurnikDepartment of Bacteriology and Immunology, Faculty of Medicine, Human Microbiome Research Program, University of Helsinki, Helsinki, Finland.
Ewa BrzozowskaHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 R. Weigl St, 53114, Wroclaw, Poland. ewa.brzozowska@hirszfeld.pl.ORCID http://orcid.org/0000-0003-0922-3625
Ludwik Hirszfeld Institute of Immunology and Experimental Therapy · PLInstitute of Physical Chemistry · PLUniversity of Wrocław · PLUniversity of Helsinki · FI

Funding

Narodowym Centrum Nauki National Science CenterNarodowym Centrum Nauki Poland (Grant Numbers UMO-2017/26/E/NZ1/00249).
6 · The paper itself

Abstract

Yersiniosis is an infectious zoonotic disease caused by two enteropathogenic species of Gram-negative genus Yersinia: Yersinia enterocolitica and Yersinia pseudotuberculosis. Pigs and other wild and domestic animals are reservoirs for these bacteria. Infection is usually spread to humans by ingestion of contaminated food. Yersiniosis is considered a rare disease, but recent studies indicate that it is overlooked in the diagnostic process therefore the infections with this bacterium are not often identified. Reliable diagnosis of Yersiniosis by culturing is difficult due to the slow growth of the bacteria easily overgrown by other more rapidly growing microbes unless selec-tive growth media is used. Phage adhesins recognizing bacteria in a specific manner can be an excellent diagnostic tool, es-pecially in the diagnosis of pathogens difficult for culturing. In this study, it was shown that Gp17, the tail fiber protein (TFP) of phage φYeO3-12, specifically recognizes only the pathogenic Yersinia enterocolitica serotype O:3 (YeO:3) bacteria. The ELISA test used in this work confirmed the specific interaction of this protein with YeO:3 and demonstrated a promising tool for developing the pathogen recognition method based on phage adhesins.

Indexed as

DiagnosticELISAPhagePhage adhesinsTail fiber proteinYersinia enterocoliticaYersiniosis

Identifiers

PMID34989907
PMCPMC8739404
OpenAlexW4205734313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.