Evidence map›Paper›PMID 34989705›Full record

SynthesisPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2022

Plasma and Platelet Transfusion Strategies in Critically Ill Children Following Noncardiac Surgery and Critically Ill Children Undergoing Invasive Procedures Outside the Operating Room: From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding.

Marisa Tucci, Gemma Crighton, Susan M Goobie, Robert T Russell, Robert I Parker, Thorsten Haas, Marianne E Nellis, Adam M Vogel, Jacques Lacroix, Paul A Stricker and 1 more

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Canadian tertiary care pediatric massive hemorrhage protocols: a survey and comprehensive national review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Marisa TucciDepartment of Pediatrics, Sainte-Justine University Hospital, University of Montreal, Montreal, QC, Canada.
Gemma CrightonDepartment of Haematology, Royal Children's Hospital, Melbourne, VIC, Australia.
Susan M GoobieDepartment of Anesthesiology, Critical Care & Pain Medicine, Boston Children's Hospital, Boston, MA.
Robert T RussellDepartment of Surgery, Division of Pediatric Surgery, Children's of Alabama, University of Alabama at Birmingham, Birmingham, AL.
Robert I ParkerDepartment of Pediatrics, Stony Brook University, Stony Brook, NY.
Thorsten HaasDepartment of Anesthesia, Zurich University Children's Hospital, Zurich, Switzerland.
Marianne E NellisDivision of Pediatric Critical Care Medicine, Department of Pediatrics, NY Presbyterian Hospital - Weill Cornell Medicine, New York, NY.
Adam M VogelDivision of Pediatric Surgery, Surgery and Pediatrics Baylor College of Medicine Texas Children's Hospital, Houston, TX.
Jacques LacroixDepartment of Pediatrics, University of Montreal, Montreal, QC, Canada.
Paul A StrickerDepartment of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Pediatric Critical Care Transfusion and Anemia EXpertise Initiative–Control/Avoidance of Bleeding (TAXI-CAB), in collaboration with the Pediatric Critical Care Blood Research Network (BloodNet), and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network
Boston Children's Hospital · USRoyal Children's Hospital · AUStony Brook University · USUniversité de Montréal · CAUniversity Children's Hospital Zurich · CHUniversity of Pennsylvania · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
TAXI-CAB: Transfusion and Anemia eXpert Initiative - Control/Avoidance of BleedingR13HL154544 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI NELLIS, MARIANNE · 2020 to 2020
$10k
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NHLBI NIH HHS R13 HL154544
6 · The paper itself

Abstract

objectivesTo present consensus statements and supporting literature for plasma and platelet transfusions in critically ill children following noncardiac surgery and critically ill children undergoing invasive procedures outside the operating room from the Transfusion and Anemia EXpertise Initiative - Control/Avoidance of Bleeding.

designSystematic review and consensus conference of international, multidisciplinary experts in platelet and plasma transfusion management of critically ill children.

settingNot applicable. PATIENTS: Critically ill children undergoing invasive procedures outside of the operating room or noncardiac surgery.

interventionsNone. MEASUREMENTS AND MAIN

resultsA panel of 10 experts developed evidence-based and, when evidence was insufficient, expert-based statements for plasma and platelet transfusions in critically ill children following noncardiac surgery or undergoing invasive procedures outside of the operating room. These statements were reviewed and ratified by the 29 Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding experts. A systematic review was conducted using MEDLINE, EMBASE, and Cochrane Library databases, from inception to December 2020. Consensus was obtained using the Research and Development/University of California, Los Angeles Appropriateness Method. Results were summarized using the Grading of Recommendations Assessment, Development, and Evaluation method. We developed eight expert consensus statements focused on the critically ill child following noncardiac surgery and 10 expert consensus statements on the critically ill child undergoing invasive procedures outside the operating room.

conclusionsEvidence regarding plasma and platelet transfusion in critically ill children in this area is very limited. The Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding Consensus Conference developed 18 pediatric specific consensus statements regarding plasma and platelet transfusion management in these critically ill pediatric populations.

Indexed as

AnemiaCritical IllnessBlood Component TransfusionChildCritical CareErythrocyte TransfusionEvidence-Based MedicineHemorrhageHumansOperating RoomsPlasmaPlatelet Transfusion

Identifiers

PMID34989705
PMCPMC8769350
OpenAlexW4205762261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.