ArticleeLife2022
Increasing stimulus similarity drives nonmonotonic representational change in hippocampus.
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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Who cites it
30 citing papers in PubMed, 50 citations in OpenAlex.
- Hippocampal mechanisms underlying the resolution of competition in memory and perception.Nature communications · 2026Article
- Condition-specific neural signatures of reactivation during post-retrieval rest: An EEG study.iScience · 2026Article
- Multisensory coding of audiovisual movies in the human hippocampus.bioRxiv : the preprint server for biology · 2026Article
- The Role of Rapid Eye Movement Sleep in Neural Differentiation of Memories in the Hippocampus.Journal of cognitive neuroscience · 2026Article
- Synthesizing images to map neural networks to the human brain.bioRxiv : the preprint server for biology · 2025Article
- Hippocampal transformations occur along dimensions of memory interference.bioRxiv : the preprint server for biology · 2025Article
- Cognitive modeling of lure discriminability in the Mnemonic Similarity Task.Behavior research methods · 2025Article
- Repulsion of hippocampal representations driven by distinct internal beliefs.Current biology : CB · 2025Article
- Visual Statistical Learning Alters Low-Dimensional Cortical Architecture.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Memory updating and the structure of event representations.Trends in cognitive sciences · 2025Review
- A simple model for Behavioral Time Scale Synaptic Plasticity (BTSP) provides content addressable memory with binary synapses and one-shot learning.Nature communications · 2025Article
- Inducing representational change in the hippocampus through real-time neurofeedback.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Article
- Differentiation and Integration of Competing Memories: A Neural Network Model.bioRxiv : the preprint server for biology · 2024Article
- Computational reconstruction of mental representations using human behavior.Nature communications · 2024Article
- Article
- Segregation-to-integration transformation model of memory evolution.Network neuroscience (Cambridge, Mass.) · 2024Article
- INDUCING REPRESENTATIONAL CHANGE IN THE HIPPOCAMPUS THROUGH REAL-TIME NEUROFEEDBACK.bioRxiv : the preprint server for biology · 2023Article
- Predictions transform memories: How expected versus unexpected events are integrated or separated in memory.Neuroscience and biobehavioral reviews · 2023Review
- Intact procedural memory and impaired auditory statistical learning in adults with dyslexia.Neuropsychologia · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
Abstract
Studies of hippocampal learning have obtained seemingly contradictory results, with manipulations that increase coactivation of memories sometimes leading to differentiation of these memories, but sometimes not. These results could potentially be reconciled using the nonmonotonic plasticity hypothesis, which posits that representational change (memories moving apart or together) is a U-shaped function of the coactivation of these memories during learning. Testing this hypothesis requires manipulating coactivation over a wide enough range to reveal the full U-shape. To accomplish this, we used a novel neural network image synthesis procedure to create pairs of stimuli that varied parametrically in their similarity in high-level visual regions that provide input to the hippocampus. Sequences of these pairs were shown to human participants during high-resolution fMRI. As predicted, learning changed the representations of paired images in the dentate gyrus as a U-shaped function of image similarity, with neural differentiation occurring only for moderately similar images.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.