ArticleJournal of diabetes2022
Association of sedentary time and carotid atherosclerotic plaques in patients with type 2 diabetes.
Article in Journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- The Impact of Cocoa Flavanols in Modulating Resting Cerebral Blood Flow During Prolonged Sitting in Healthy Young and Older Adults.Nutrients · 2025Trial
- Impact of MMC-assisted glycemic control assistant on biochemical indicators of glucose metabolism in type 2 diabetes: A retrospective study.Journal of medical biochemistry · 2026Article
- Development and validation of a machine learning-based predictive model for carotid plaque in type 2 diabetes.Frontiers in cardiovascular medicine · 2026Article
- Age and Gender Difference in the Association of Metabolic Syndrome and Peripheral Artery Disease Among Patients With Type 2 Diabetes Mellitus.International journal of vascular medicine · 2025Article
- The Relationship Between Age at Diabetes Onset and Clinical Outcomes in Newly Diagnosed Type 2 Diabetes: A Real-World Two-Center Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- The effects of economic status on metabolic control in type 2 diabetes mellitus at 10 metabolic management centers in China.Journal of diabetes · 2024Article
- Differences in Associated Factors of Sedentary Behavior by Diabetes Mellitus Status: A Nationwide Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Replacing of sedentary behavior with physical activity and the risk of mortality in people with prediabetes and diabetes: a prospective cohort study.The international journal of behavioral nutrition and physical activity · 2023Article
- The Chinese Metabolic Management Centers.Journal of diabetes · 2022Article
- MMC celebrating 6 years of experience and expansion.Journal of diabetes · 2022Article
- Follow-up frequency and clinical outcomes in patients with type 2 diabetes: A prospective analysis based on multicenter real-world data.Journal of diabetes · 2022Article
- Association of sedentary time and carotid atherosclerotic plaques in patients with type 2 diabetes.Journal of diabetes · 2022Article
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Authors and funding
16 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtherosclerosis is a common complication in patients with type 2 diabetes (T2DM). Multiple factors are involved in the development and progress of atherosclerosis. We evaluated the association of weekly sedentary time (WST) with carotid plaque formation.
methodsAfter data cleaning, a total of 26 664 participants with T2DM from 10 National Metabolic Management Centers (MMCs) from June 2017 to April 2021 were enrolled. Self-reported lifestyle data including WST, sleeping time, smoking and drinking information, carotid artery ultrasound, and biochemical parameters were obtained. The independent association of carotid plaue with sedentary and other lifestyle behaviors was evaluated using multivariable logistic regression models, and odds ratio (OR) with 95% confidence interval (CI) were reported. Moreover, stratified analysis was conducted to demonstrate the influence of confounding factors.
resultsThe mean (SD) age of the participants was 54.0 (11.6) years, and the median (interquartile range) WST was 35.0 (21.0, 42.0) h. Comparing with participants in the first tertile of WST, those in the second or third tertile of WST were younger and with a shorter duration of diabetes. There were positive associations between longer sedentary time and odds of artery plaque after adjustment, with corresponding ORs in the second and third tertile were 1.40 (95% CI: 1.31-1.50) and 1.67 (95% CI: 1.56-1.79), respectively. However, the effect of WST on plaque in patients aged 18-40 years old had no statistical significance; the p value in the third tertile was 0.163.
conclusionsIn summary, higher WST appears to be associated with higher prevalence of carotid plaque in patients with T2DM, especially in aged populations.
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