Evidence map›Paper›PMID 34989139›Full record

ArticleInfluenza and other respiratory viruses2022

Incidence of medically attended influenza and influenza virus infections confirmed by serology in Ningbo City from 2017-2018 to 2019-2020.

Cuiling Xu, Xuying Lao, Hongyu Li, Libo Dong, Shumei Zou, Yi Chen, Yongquan Gu, Yueqin Zhu, Pingfeng Xuan, Weijuan Huang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Cuiling XuChinese National Influenza Center, National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health Commission, Beijing, P.R. China.ORCID 0000-0002-2269-7772
Xuying LaoNingbo Municipal Center for Disease Prevention and Control, Ningbo, P.R. China.
Hongyu LiLaboratory of Microbiology, Gansu Provincial Center for Disease Control and Prevention, Lanzhou, P.R. China.
Libo DongChinese National Influenza Center, National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health Commission, Beijing, P.R. China.
Shumei ZouChinese National Influenza Center, National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health Commission, Beijing, P.R. China.
Yi ChenNingbo Municipal Center for Disease Prevention and Control, Ningbo, P.R. China.
Yongquan GuYuyao Municipal Center for Disease Prevention and Control, Ningbo, P.R. China.
Yueqin ZhuLanjiang Street Community Health Service Center, Ningbo, P.R. China.
Pingfeng XuanYangming Street Community Health Service Center, Ningbo, P.R. China.
Weijuan HuangChinese National Influenza Center, National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health Commission, Beijing, P.R. China.
Dayan WangChinese National Influenza Center, National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health Commission, Beijing, P.R. China.ORCID 0000-0002-4990-1016
Bo YiNingbo Municipal Center for Disease Prevention and Control, Ningbo, P.R. China.ORCID 0000-0001-5997-852X
National Institute for Viral Disease Control and Prevention · CNNingbo Center for Disease Control and Prevention · CNCommunity Health Center · USGansu Provincial Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn mainland China, the disease burden of influenza is not yet fully understood. Based on population-based data, we aimed to estimate incidence rates of medically attended influenza and influenza virus infections in Ningbo City.

methodsWe used data for outpatient acute respiratory illness (OARI) from a platform covering all health and medical institutes in Yingzhou District, Ningbo City. We applied generalized additive regression models to estimate influenza-associated excess incidence rate of OARI by age. We recruited local residents aged ≥60 years in the autumn of 2019 and conducted follow-up nearly 9 months later. Every survey, the sera were collected for testing hemagglutination inhibition antibody.

resultsFrom 2017-2018 to 2019-2020, the annual average of influenza-associated incidence rate of OARI in all ages was 10.9%. The influenza-associated incidence rate of OARI was the highest in 2017-2018 (16.9%) and the lowest in 2019-2020 (4.8%). Regularly, influenza-associated incidence rates of OARI were the highest in children aged 5-14 years (range: 44.1-77.6%) and 0-4 years (range: 8.3-46.6%). The annual average of excess OARI incidence rate in all ages was the highest for influenza B/Yamagata (3.9%). The overall incidence rate of influenza infections indicated by serology in elderly people was 21% during the winter season of 2019-2020.

conclusionsWe identified substantial outpatient influenza burden in all ages in Ningbo. Our cohort study limited in elderly people found that this age group had a high risk of seasonal influenza infections. Our study informs the importance of increasing influenza vaccine coverage in high-risk population including elderly people.

Indexed as

Influenza, HumanInfluenza VaccinesAdolescentAgedChildChild, PreschoolCohort StudiesHumansIncidenceInfantMiddle AgedSeasonsInfluenza Vaccinesacute respiratory illnessburden of diseaseChinaincidence ratesinfectioninfluenza

Identifiers

PMID34989139
PMCPMC8983918
OpenAlexW4205726591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.