Evidence map›Paper›PMID 34989092›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2022

Prevalence of carbapenemase-producing organisms among hospitalized solid organ transplant recipients, five US hospitals, 2019-2020.

June L Chan, Elizabeth Nazarian, Kimberlee A Musser, Emily A Snavely, Monica Fung, Sarah B Doernberg, Stephanie M Pouch, Surbhi Leekha, Judith A Anesi, Rosy Priya L Kodiyanplakkal and 3 more

Abstract read
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Desirability of outcome ranking and quality life measurement for antimicrobial research in organ transplantation.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

June L ChanBacterial Diseases Laboratory, New York State Department of Health, Wadsworth Center, Albany, New York, USA.ORCID https://orcid.org/0000-0002-5435-5558
Elizabeth NazarianBacterial Diseases Laboratory, New York State Department of Health, Wadsworth Center, Albany, New York, USA.
Kimberlee A MusserBacterial Diseases Laboratory, New York State Department of Health, Wadsworth Center, Albany, New York, USA.
Emily A SnavelyBacterial Diseases Laboratory, New York State Department of Health, Wadsworth Center, Albany, New York, USA.
Monica FungDepartment of Medicine, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0002-1725-5259
Sarah B DoernbergDepartment of Medicine, University of California San Francisco, San Francisco, California, USA.
Stephanie M PouchDepartment of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Surbhi LeekhaDepartment of Epidemiology and Public Health, University of Maryland Medical Center, Baltimore, Maryland, USA.
Judith A AnesiDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-6671-4557
Rosy Priya L KodiyanplakkalDepartment of Medicine, Weill Cornell Medicine, New York, New York, USA.
Sarah E TurbettDepartment of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Maroya Spalding WaltersDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Lauren EpsteinDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Funding

CDC HHS NU50CK000423CDC HHS U60OE000103Intramural CDC HHS CC999999NCEZID CDC HHS U50 CK000423OSELS CDC HHS U60 OE000103
6 · The paper itself

Abstract

backgroundPassive reporting to the Centers for Disease Control and Prevention has identified carbapenemase-producing organisms (CPOs) among solid organ transplant (SOT) recipients, potentially representing an emerging source of spread. We analyzed CPO prevalence in wards where SOT recipients receive inpatient care to inform public health action to prevent transmission.

methodsFrom September 2019 to June 2020, five US hospitals conducted consecutive point prevalence surveys (PPS) of all consenting patients admitted to transplant units, regardless of transplant status. We used the Cepheid Xpert Carba-R assay to identify carbapenemase genes (bla

resultsIn total, 154 patients were screened and 92 (60%) were SOT recipients. CPOs were detected among 7 (8%) SOT recipients, from two of five screened hospitals: four bla

conclusionsLongitudinal surveillance in transplant units, as well as PPS in areas with diverse CPO epidemiology, may inform the utility of routine screening in SOT units to prevent the spread of CPOs.

Indexed as

beta-LactamasesOrgan TransplantationBacterial ProteinsHospitalsHumansPrevalenceRetrospective StudiesTransplant RecipientsBacterial Proteinsbeta-Lactamasescarbapenemasecarbapenemase-producing organismpoint prevalence surveysolid organ transplant

Identifiers

PMID34989092
PMCPMC11318107

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.