Evidence map›Paper›PMID 34989019›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2022

Knee joint biomechanics during gait improve from 3 to 6 months after anterior cruciate ligament reconstruction.

Kelsey Neal, Jack R Williams, Abdulmajeed Alfayyadh, Jacob J Capin, Ashutosh Khandha, Kurt Manal, Lynn Snyder-Mackler, Thomas S Buchanan

Abstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
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  5. Review
  6. Review
  7. Bilateral waveform analysis of gait biomechanics presurgery to 12 months following ACL reconstruction compared to controls.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kelsey NealDepartment of Mechanical Engineering, University of Delaware, Newark, Delaware, USA.ORCID 0000-0002-1347-0648
Jack R WilliamsDepartment of Mechanical Engineering, University of Delaware, Newark, Delaware, USA.ORCID 0000-0002-9029-1029
Abdulmajeed AlfayyadhBiomechanics and Movement Science, University of Delaware, Newark, Delaware, USA.
Jacob J CapinBiomechanics and Movement Science, University of Delaware, Newark, Delaware, USA.
Ashutosh KhandhaDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware, USA.ORCID 0000-0001-6003-3881
Kurt ManalDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, USA.
Lynn Snyder-MacklerBiomechanics and Movement Science, University of Delaware, Newark, Delaware, USA.
Thomas S BuchananDepartment of Mechanical Engineering, University of Delaware, Newark, Delaware, USA.

Funding

ACL Reconstructed Knee: qMRI and Biomechanical ModelingR01HD087459 · NICHD · UNIVERSITY OF DELAWARE · PI BUCHANAN, THOMAS S · 2016 to 2020
$1.8M
Contralateral Knee Osteoarthritis Among Older Adults after Primary Total Knee ArthroplastyF32AG066274 · NIA · UNIVERSITY OF COLORADO DENVER · PI CAPIN, JACOB J · 2019 to 2021
$94k
Walking Mechanics, Early Osteoarthritis Development, and Neuromuscular Training after Traumatic Knee InjuryF30HD096830 · NICHD · UNIVERSITY OF DELAWARE · PI CAPIN, JACOB J · 2018 to 2019
$53k
NIA NIH HHS F32 AG066274NICHD NIH HHS F30 HD096830NICHD NIH HHS R01 HD087459
6 · The paper itself

Abstract

Gait alterations after anterior cruciate ligament reconstruction (ACLR) are commonly reported and have been linked to posttraumatic osteoarthritis development. While knee gait alterations have been studied at several time points after ACLR, little is known about how these biomechanical variables change earlier than 6 months after surgery, nor is much known about how they differ over the entire stance phase of gait. The purpose of this study was to examine knee gait biomechanical variables over their entire movement pattern through stance at both 3 and 6 months after ACLR and to study the progression of interlimb asymmetry between the two postoperative time points. Thirty-five individuals underwent motion analysis during overground walking 3 (3.2 ± 0.5) and 6 (6.4 ± 0.7) months after ACLR. Knee biomechanical variables were compared between limbs and across time points through 100% of stance using statistical parametric mapping; this included a 2 × 2 (Limb × Time) repeated measures analysis of variance and two-tailed t-tests. Smaller knee joint angles, moments, extensor forces, and medial compartment forces were present in the involved versus uninvolved limb. Interlimb asymmetries were present at both time points but were less prevalent at 6 months. The uninvolved limb's biomechanical variables stayed relatively consistent over time, while the involved limb's trended toward that of the uninvolved limb. Statement of Clinical Significance: Interventions to correct asymmetrical gait patterns after ACLR may need to occur early after surgery and may need to focus on multiple parts of stance phase.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionBiomechanical PhenomenaGaitHumansKnee JointACLRgait biomechanicskinematics and kineticskneestatistical parametric mapping

Identifiers

PMID34989019
PMCPMC9256843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.