ArticleArchives of gynecology and obstetrics2022
The colonized microbiota composition in the peritoneal fluid in women with endometriosis.
Article in Archives of gynecology and obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Gut and Vaginal Microbiota in the Endometriosis: Systematic Review and Meta-Analysis.BioMed research international · 2023Pooled it
- Increased C-Reactive Protein Concentrations During Menstruation May Be Important for the Pathophysiology of Endometriosis and Possibly for Adhesion Formation-A Systematic Review.Journal of clinical medicine · 2026Review
- Mechanistic insights into endometriosis: roles of Streptococcus agalactiae and L-carnitine in lesion development and angiogenesis.Angiogenesis · 2025Article
- Gut microbiome in patients with early-stage and late-stage endometriosis.BMC women's health · 2025Article
- A Potential Link Between Oral Microbiota and Female Reproductive Health.Microorganisms · 2025Review
- Oral, Vaginal, and Stool Microbial Signatures in Patients With Endometriosis as Potential Diagnostic Non-Invasive Biomarkers: A Prospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Broadening horizons: microbiota as a novel biomarker and potential treatment for endometriosis.Frontiers in microbiology · 2025Review
- Pathogenic mechanisms and therapeutic potential of the microbiome in premature ovarian insufficiency.Frontiers in immunology · 2025Review
- Microbiome dysbiosis and endometriosis: a systematic scoping review of current literature and knowledge gaps.Human reproduction open · 2025Review
- Menstrual products: culprits or bystanders in endometriosis and adenomyosis pathogenesis?Archives of gynecology and obstetrics · 2024Review
- Endometriosis, Pain, and Related Psychological Disorders: Unveiling the Interplay among the Microbiome, Inflammation, and Oxidative Stress as a Common Thread.International journal of molecular sciences · 2024Review
- Nanopore-based metagenomics analysis reveals microbial presence in amniotic fluid: A prospective study.Heliyon · 2024Article
- Comparison of microbial abundance and diversity in uterine and peritoneal fluid in infertile patients with or without endometriosis.BMC women's health · 2024Article
- Review
- Endometriosis is a disease of immune dysfunction, which could be linked to microbiota.Frontiers in genetics · 2024Article
- Unraveling the microbial puzzle: exploring the intricate role of gut microbiota in endometriosis pathogenesis.Frontiers in cellular and infection microbiology · 2024Review
- Current Updates on the Role of Microbiome in Endometriosis: A Narrative Review.Microorganisms · 2023Review
- Gut microbiota and microbiota-derived metabolites promotes endometriosis.Cell death discovery · 2023Article
- Rare case ofClinical nephrology. Case studies · 2023Article
- Female reproductive health impacts of Long COVID and associated illnesses including ME/CFS, POTS, and connective tissue disorders: a literature review.Frontiers in rehabilitation sciences · 2023Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe imbalance of microbiome in vivo is believed to be involved in the pathogenicity of endometriosis. This study aimed to investigate and analyze the composition of bacterial communities in the peritoneal fluid of women with endometriosis.
methodsTo collect peritoneal fluid samples from women with (N = 36) and without (N = 25) endometriosis in a generalized hospital in Hunan, China during January to December of 2019. Genomic DNA was extracted from peritoneal fluid samples, and targeted amplified for the V4 region of 16S ribosomal RNA gene followed by amplicon sequencing. Non-parametric Wilcoxon rank-sum test and chi-squared test were used to compare and analysis the difference between groups.
resultsAnalysis showed that microbiota diversity was similar in the peritoneal fluid of women with or without endometriosis. Ralstonia mainly dominated in the peritoneal fluid of patients in both groups, with an overall relative abundance of 11.15% (95% CI: 10.51-11.80%) in endometriosis patients, followed by Acinetobacter, Pseudomonas, Asticcacaulis, and Methyloversatilis, with no significant difference between endometriosis patients and the control group. Nevertheless, there were microbes with different abundance in peritoneal fluid of the two groups, and the relative abundance was less than 0.5%. Acidovorax (P = 0.01), Devosia (P = 0.03), Methylobacterium (P = 0.03), Phascolarctobacterium (P = 0.03), and Streptococcus (P = 0.04) were more abundant in the peritoneal fluid of endometriosis patients than the controls, while Brevundimonas (P = 0.01) and Stenotrophomonas (P = 0.04) were less abundant.
conclusionThe composition of minority microbiota including Acidovorax, Devosia, Methylobacterium, Phascolarctobacterium, and Streptococcus in peritoneal fluid were found to change among women with endometriosis. Further research is needed to explore the mechanisms of these microorganisms in the pathophysiology of endometriosis.
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