Evidence map›Paper›PMID 34988595›Full record

ArticleCalcified tissue international2022

Expression Profiling of Selected Immune Genes and Trabecular Microarchitecture in Breast Cancer Skeletal Metastases Model: Effect of α-Tocopherol Acetate Supplementation.

Riadh Badraoui, Mohd Saeed, Nouha Bouali, Walid S Hamadou, Salem Elkahoui, Mohammad J Alam, Arif J Siddiqui, Mohd Adnan, Mongi Saoudi, Tarek Rebai

Abstract read
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In one paragraph

Article in Calcified tissue international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

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  6. Metabolomic evaluation of air pollution-related bone damage and potential mediation in Women's Health Initiative participants.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
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  7. Anti-methanogenic effect of phytogenic extract ofJournal of advanced veterinary and animal research · 2025
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  15. Molecules (Basel, Switzerland) · 2023
    Article
  16. Article
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  18. Chemical Composition ofMetabolites · 2022
    Article
  19. Physiological Responses of the BivalvesAnimals : an open access journal from MDPI · 2022
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  20. Life (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Riadh BadraouiLaboratory of General Biology, Department of Biology, University of Ha'il, Ha'il, 81451, Saudi Arabia. badraouir@yahoo.fr.ORCID 0000-0001-9054-7744
Mohd SaeedLaboratory of General Biology, Department of Biology, University of Ha'il, Ha'il, 81451, Saudi Arabia.
Nouha BoualiLaboratory of General Biology, Department of Biology, University of Ha'il, Ha'il, 81451, Saudi Arabia.
Walid S HamadouLaboratory of General Biology, Department of Biology, University of Ha'il, Ha'il, 81451, Saudi Arabia.
Salem ElkahouiLaboratory of General Biology, Department of Biology, University of Ha'il, Ha'il, 81451, Saudi Arabia.
Mohammad J AlamLaboratory of General Biology, Department of Biology, University of Ha'il, Ha'il, 81451, Saudi Arabia.
Arif J SiddiquiLaboratory of General Biology, Department of Biology, University of Ha'il, Ha'il, 81451, Saudi Arabia.
Mohd AdnanLaboratory of General Biology, Department of Biology, University of Ha'il, Ha'il, 81451, Saudi Arabia.
Mongi SaoudiLaboratory Animal Physiology, Department of Biology, College of Science, University of Sfax, 3045, Sfax, Tunisia.
Tarek RebaiLaboratory of Histo-Embryology and Cytogenetics, Medicine Faculty of Sfax, University of Sfax, 3029, Sfax, Tunisia.
University of Ha'il · SAUniversity of Sfax · TNTunis University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer bone metastases (BCBM) result in serious skeletal morbidity. Although there have been important advances in cancer treatment methods such as surgery and chemotherapy, the complementary treatments, such as α-tocopherol acetate (ATA), still remain of key role via complementary and/or synergistic effects. The aim of this work was to study immune response in a rat model of BCBM due to Walker 256/B cells inoculation and the effect of ATA alone. Compared to the control group (CTRL), rat injected with Walker 256/B cells (5 × 10

Indexed as

alpha-TocopherolBreast NeoplasmsOsteolysisAnimalsBone NeoplasmsCyclooxygenase 2Dietary SupplementsRatsTumor Necrosis Factor-alphaX-Ray Microtomographyalpha-TocopherolCyclooxygenase 2Tumor Necrosis Factor-alphaBone metastasesCOX-2MicroarchitectureTNF-αWalker 256/B malignant breast cancerα-Tocopherol acetate

Identifiers

PMID34988595
OpenAlexW4205946442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.