Evidence map›Paper›PMID 34988591›Full record

ArticleAnalytical and bioanalytical chemistry2022

A novel graphene oxide/chitosan foam incorporated with metal-organic framework stationary phase for simultaneous enrichment of glycopeptide and phosphopeptide with high efficiency.

Rong Liu, Wenqing Gao, Jiaqian Yang, Shun Zhang, Chenlu Wang, Jing Lin, Sijia Zhang, Jiancheng Yu, Keqi Tang

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rong LiuKey Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, People's Republic of China.
Wenqing GaoKey Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, People's Republic of China. gaowenqing@nbu.edu.cn.ORCID http://orcid.org/0000-0002-1970-5655
Jiaqian YangKey Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, People's Republic of China.
Shun ZhangNingbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, People's Republic of China.
Chenlu WangKey Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, People's Republic of China.
Jing LinNingbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, People's Republic of China.
Sijia ZhangNingbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, People's Republic of China.
Jiancheng YuFaculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo, People's Republic of China. yujiancheng@nbu.edu.cn.
Keqi TangKey Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, People's Republic of China. tangkeqi@nbu.edu.cn.
Ningbo University · CNKey Laboratory of Guangdong Province · CN

Funding

K.C. Wong Magna Fund in Ningbo University xkzwl1507Key Research and Development Program of Zhejiang Province 2020C03064National Natural Science Foundation of China 61971248National Natural Science Foundation of China U20A20121Open Funds of Key Laboratory of Diagnosis and Treatment of Digestive System Tumors of Zhejiang Province KFJJ-202102Science and Technology Major Project of Ningbo 2018B10075
6 · The paper itself

Abstract

A novel hydrophilic porous biocomposite was fabricated by incorporating graphene oxide (GO) @chitosan (CS) foam substrate (GO@CS@ZIF-8 foam) with ZIF-8 crystals in situ via a facile stirring method for simultaneous enrichment of glycopeptides and phosphopeptides from complex biological samples. The experimental results demonstrated that GO@CS@ZIF-8 foam exhibited favorable specificity for simultaneous enrichment of N-glycopeptides and phosphopeptides under the same condition for HRP and β-casein tryptic digest mixtures. The novel material was further applied to enriching both glycopeptides and phosphopeptides simultaneously from 4 μL complex human serum, and 423 N-glycopeptides and 40 phosphopeptides corresponding to 133 glycoproteins and 29 phosphoproteins were identified, respectively.

Indexed as

ChitosanMetal-Organic FrameworksGlycopeptidesGraphiteHumansHydrophobic and Hydrophilic InteractionsPhosphopeptidesChitosanGlycopeptidesgraphene oxideGraphiteMetal-Organic FrameworksPhosphopeptidesFoamGlycopeptides enrichmentHydrophilic porous biocompositeMass spectrometryPhosphopeptides enrichment

Identifiers

PMID34988591
OpenAlexW4205859576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.