Evidence map›Paper›PMID 34988540›Full record

ArticleJournal of affective disorders reports2021

Comparison of depression and anxiety symptom networks in reporters and non-reporters of lifetime trauma in two samples of differing severity.

Alicia J Peel, Chérie Armour, Joshua E J Buckman, Jonathan R I Coleman, Susannah C B Curzons, Molly R Davies, Christopher Hübel, Ian Jones, Gursharan Kalsi, Monika McAtarsney-Kovacs and 11 more

Open access · goldAbstract read
In one paragraph

Article in Journal of affective disorders reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. The Network Model of Mentalization, Social Vulnerability, and the Self in Autism: A Comparison With Neurotypical Adults.Autism research : official journal of the International Society for Autism Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 2 countries.

Alicia J PeelSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Chérie ArmourSchool of Psychology, Queens University Belfast, Belfast BT7 1NN, Northern Ireland.
Joshua E J BuckmanCentre for Outcomes Research and Effectiveness (CORE), Research Department of Clinical, Educational & Health Psychology, University College London, London WC1E 7HB, UK.
Jonathan R I ColemanSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Susannah C B CurzonsSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Molly R DaviesSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Christopher HübelSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Ian JonesNational Centre for Mental Health, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff CF24 4HQ, UK.
Gursharan KalsiSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Monika McAtarsney-KovacsSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Andrew M McIntoshDivision of Psychiatry, University of Edinburgh, Edinburgh EH10 5HF, UK.
Dina MonssenSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Jessica MundySocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Christopher RaynerSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Henry C RogersSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Megan SkeltonSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Abigail Ter KuileSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Katherine N ThompsonSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Gerome BreenSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Andrea DaneseSocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
Thalia C EleySocial, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience; King's College London, London SE5 8AF, UK.
King's College London · GBNational Institute for Health Research · GBCentre for Mental Health · GBKarolinska Institutet · SESouth London and Maudsley NHS Foundation Trust · GBUniversity College London · GBUniversity of Edinburgh · GB

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853Medical Research Council MR/V012878/1
6 · The paper itself

Abstract

backgroundReported trauma is associated with differences in the course and outcomes of depression and anxiety. However, no research has explored the association between reported trauma and patterns of clinically relevant symptoms of both depression and anxiety.

methodsWe used network analysis to investigate associations between reported trauma and depression and anxiety symptom interactions in affected individuals from the Genetic Links to Anxiety and Depression (GLAD) Study (n = 17720), and population volunteers from the UK Biobank (n = 11120). Participants with current moderate symptoms of depression or anxiety were grouped into reporters and non-reporters of lifetime trauma. Networks of 16 depression and anxiety symptoms in the two groups were compared using the network comparison test.

resultsIn the GLAD Study, networks of reporters and non-reporters of lifetime trauma did not differ on any metric. In the UK Biobank, the symptom network of reporters had significantly greater density (7.80) than the network of non-reporters (7.05). LIMITATIONS: The data collected in the GLAD Study and the UK Biobank are self-reported with validated or semi-validated questionnaires.

conclusionsReported lifetime trauma was associated with stronger interactions between symptoms of depression and anxiety in population volunteers. Differences between reporters and non-reporters may not be observed in individuals with severe depression and/or anxiety due to limited variance in the presentation of disorder.

Indexed as

AnxietyDepressionNetwork analysisSelf-reportTrauma

Identifiers

PMID34988540
PMCPMC8689407
OpenAlexW3184123993

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.