Evidence map›Paper›PMID 34988504›Full record

ArticleHeart rhythm O22021

Assessing long-term survival and hospitalization following transvenous lead extraction in patients with cardiac resynchronization therapy devices: A propensity score-matched analysis.

Vishal S Mehta, Hugh O'Brien, Mark K Elliott, Baldeep S Sidhu, Justin Gould, Anoop K Shetty, Steven Niederer, Christopher A Rinaldi

Open access · goldAbstract read
In one paragraph

Article in Heart rhythm O2, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vishal S MehtaCardiology Department, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Hugh O'BrienSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Mark K ElliottCardiology Department, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Baldeep S SidhuCardiology Department, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Justin GouldCardiology Department, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Anoop K ShettyCardiology Department, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Steven NiedererSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Christopher A RinaldiCardiology Department, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
King's College London · GBGuy's and St Thomas' NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLonger-term outcomes of patients post transvenous lead extraction (TLE) are poorly understood in patients with cardiac resynchronization therapy (CRT) devices.

objectivesA propensity score (PS)-matched analysis evaluating outcomes post TLE in CRT and non-CRT populations was performed.

methodsData from consecutive patients undergoing TLE between 2000 and 2019 were prospectively collected. Patients surviving to discharge and reimplanted with the same device were included. The cohort was split depending on presence of CRT device. Associations with all-cause mortality and hospitalization were assessed by Kaplan-Meier estimates. An exploratory endpoint was evaluated whether early (<7 days) or late (>7 days) reimplantation was associated with poorer outcomes.

resultsOf 1005 patients included, 285 (25%) had a CRT device. Median follow-up was 57.00 [27.00-93.00] months, age at explant was 67.7 ± 12.1 years, 83.3% were male, and 54.4% had an infective indication for TLE. PS was calculated using 43 baseline characteristics. After matching, 192 CRT patients were compared with 192 non-CRT patients. In the matched cohort, no significant difference with respect to mortality (hazard ratio [HR] = 1.01, 95% confidence interval [CI] [0.74-1.39],

conclusionOutcomes of CRT patients post TLE are similarly as poor as those of non-CRT patients in matched populations. Reimplantation within 7 days was associated with better outcomes in a CRT population but was not observed in a non-CRT population, suggesting prolonged periods without biventricular pacing should be avoided.

Indexed as

Cardiac resynchronization therapyCRTHospitalizationMortalityPropensity score matchingTransvenous lead extraction

Identifiers

PMID34988504
PMCPMC8703147
OpenAlexW3211023268

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.