Evidence map›Paper›PMID 34988472›Full record

ReviewJACC. CardioOncology2021

Cardiac Computed Tomography in Cardio-Oncology:

Juan C Lopez-Mattei, Eric H Yang, Maros Ferencik, Lauren A Baldassarre, Susan Dent, Matthew J Budoff

Open access · goldAbstract readReview
In one paragraph

Review in JACC. CardioOncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. [European journal of nuclear medicine and molecular imaging · 2025
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Advancing cardiac tumor diagnosis: evaluatingAmerican journal of cardiovascular disease · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Cardio-Oncology and Multi-Imaging Modalities.Journal of clinical medicine · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Juan C Lopez-MatteiHeart and Vascular Institute, Lee Health System, Fort Myers, Florida, USA.
Eric H YangUCLA Cardio-Oncology Program, Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, California, USA.
Maros FerencikKnight Cardiovascular Institute, Oregon Health and Science University, Portland, Oregon, USA.
Lauren A BaldassarreSection of Cardiovascular Medicine, Department of Medicine and Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut, USA.
Susan DentDuke Cancer Institute, Department of Medicine, Duke University, Durham, North Carolina, USA.
Matthew J BudoffDepartment of Medicine, Lundquist Institute at Harbor UCLA Medical Center, Torrance, California, USA.
Duke University · USLee Memorial Health System · USOregon Health & Science University · USUCLA Medical Center · USUniversity of California, Los Angeles · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Cancer patients and survivors have elevated cardiovascular risk when compared with noncancer patients. Cardio-oncology has emerged as a new subspecialty to comanage and address cardiovascular complications in cancer patients such as heart failure, atherosclerotic cardiovascular disease (ASCVD), valvular heart disease, pericardial disease, and arrhythmias. Cardiac computed tomography (CT) can be helpful in identifying both clinical and subclinical ASCVD in cancer patients and survivors. Radiation therapy treatment planning CT scans and cancer staging/re-staging imaging studies can quantify calcium scores which can identify pre-existing subclinical ASCVD. Cardiac CT can be helpful in the evaluation of cardiac tumors and pericardial diseases, especially in patients who cannot tolerate or have a contraindication to cardiac magnetic resonance. In this review, we describe the optimal utilization of cardiac CT in cancer patients, including risk assessment for ASCVD and identification of cancer treatment-related cardiovascular toxicity.

Indexed as

ASCVD, atherosclerotic cardiovascular diseaseatherosclerotic cardiovascular diseasecalcium score cardio-oncologycarcinoid syndromecardiotoxicitycardiovascular computed tomographyCT, computed tomographyPET, positron emission tomographyradiation therapyRT, radiation therapyTEE, transesophageal echocardiographyTTE, transthoracic echocardiography

Identifiers

PMID34988472
PMCPMC8702811
OpenAlexW4200492500

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.