Evidence map›Paper›PMID 34988342›Full record

ArticlePathogens & immunity2021

A Patient With Multiple Carbapenemase Producers Including an Unusual

Aline I Moser, Peter M Keller, Edgar I Campos-Madueno, Laurent Poirel, Patrice Nordmann, Andrea Endimiani

Open access · diamondAbstract read
In one paragraph

Article in Pathogens & immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Within patient horizontal gene transfer dynamics of a blaEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Plasmid diversity ofMicrobiology spectrum · 2025
    Article
  6. Article
  7. Genomic surveillance detects interregional spread of New Delhi metallo-beta-lactamase-1-producingEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  8. Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2024
    Review
  9. Genome-Based Retrospective Analysis of aAntibiotics (Basel, Switzerland) · 2023
    Article
  10. A brief insight intoFrontiers in antibiotics · 2023
    Review
  11. Klebsiella pneumoniae ST147: and then there were three carbapenemases.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aline I MoserInstitute for Infectious Diseases (IFIK), University of Bern, Bern, Switzerland.
Peter M KellerInstitute for Infectious Diseases (IFIK), University of Bern, Bern, Switzerland.
Edgar I Campos-MaduenoInstitute for Infectious Diseases (IFIK), University of Bern, Bern, Switzerland.
Laurent PoirelEmerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland.
Patrice NordmannEmerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland.
Andrea EndimianiInstitute for Infectious Diseases (IFIK), University of Bern, Bern, Switzerland.
University of Bern · CHUniversity of Fribourg · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients colonized with multiple species of carbapenemase-producing Enterobacterales (CPE) are increasingly observed. This phenomenon can be due to the high local prevalence of these pathogens, the presence of important host risk factors, and the great genetic promiscuity of some carbapenemase genes.

methodsWe analyzed 4 CPE (

resultsAll CPE presented high-level resistance to all aminoglycosides due to the expression of the

conclusionsThe characterization of the genetic organization of IncC-type plasmids harbored by 3 different species from the same patient offered insights into the evolution of these broad-host-range plasmids. Moreover, we characterized here the first complete genome sequence of a carbapenemase-producing

Indexed as

ArmAcarbapenemasesCPEEnterobacteralesNDM-1plasmid

Identifiers

PMID34988342
PMCPMC8714174
OpenAlexW3217576158

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.