Evidence map›Paper›PMID 34988220›Full record

ArticleERJ open research2021

Lung cancer mortality in Europe and the USA between 2000 and 2017: an observational analysis.

Chinmay Jani, Dominic C Marshall, Harpreet Singh, Richard Goodall, Joseph Shalhoub, Omar Al Omari, Justin D Salciccioli, Carey C Thomson

Abstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Translational cancer research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chinmay JaniDept of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA, USA.ORCID https://orcid.org/0000-0002-6917-5568
Dominic C MarshallNational Heart and Lung Institute, Imperial College London, London, UK.
Harpreet SinghDept of Pulmonary and Critical Care, Medical College of Wisconsin, Milwaukee, WI, USA.
Richard GoodallDept of Surgery and Cancer, Imperial College of London, London, UK.
Joseph ShalhoubDept of Surgery and Cancer, Imperial College of London, London, UK.
Omar Al OmariDept of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA, USA.
Justin D SalciccioliHarvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0001-8092-0883
Carey C ThomsonDept of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe lung is the most common site for cancer and has the highest worldwide cancer-related mortality. Our study reports and compares trends in lung cancer mortality in the USA and 26 European countries. STUDY DESIGN AND

methodsLung cancer mortality data were extracted for males and females for each of the years 2000-2017 from the World Health Organization (WHO) Mortality and the Centers for Disease Control and Prevention (CDC) WONDER databases. Lung cancer mortality trends were compared using Joinpoint regression analysis, and male-to-female mortality ratios were calculated.

resultsDown-trending lung cancer mortality rates were observed in males in all countries except Cyprus and Portugal between 2000 and 2017. In females, increasing mortality rates were observed in 22 of the 27 countries analysed. Latvia had the highest estimated annual percentage change (EAPC) in male mortality (-9.6%) between 2013 and 2015. In the USA, EAPCs were -5.1% for males and -4.2% for females between 2014 and 2017. All countries had an overall decrease in the ratio of male-to-female lung cancer mortality. The most recent observation of median male-to-female mortality was 2.26 (IQR 1.92-4.05). The countries with the greatest current sex disparity in lung cancer mortality were Lithuania (5.51) and Latvia (5.00).

conclusionBetween 2000 and 2017, lung cancer mortality rates were decreasing for males in Europe and the USA, whereas increasing lung cancer mortality rates were generally observed in females. There is a persistent but decreasing sex-mortality gap, with men having persistently greater lung cancer mortality but with rates decreasing faster than women.

Identifiers

PMID34988220
PMCPMC8711085

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.