Evidence map›Paper›PMID 34988202›Full record

ArticleAnnals of translational medicine2021

Y-box binding protein 1 regulates liver lipid metabolism by regulating the Wnt/β-catenin signaling pathway.

Zhenzeng Ma, Yu Zhu, Qizhi Wang, Min Deng, Jianchao Wang, Dapeng Li, Lin Gu, Rui Zhao, Shanjun Yan

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhenzeng MaDepartment of Gastroenterology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Yu ZhuDepartment of Gastroenterology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Qizhi WangDepartment of Gastroenterology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Min DengDepartment of Gastroenterology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Jianchao WangDepartment of Gastroenterology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Dapeng LiDepartment of Gastroenterology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Lin GuDepartment of Gastroenterology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Rui ZhaoDepartment of Gastroenterology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Shanjun YanDepartment of Gastroenterology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
First Affiliated Hospital of Bengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe mainly investigated how y-box binding protein 1 (

methodsThe LO2 cells were treated with palmitic acid (PA) to create an NAFLD model

resultsWe found that

conclusionsIn summary, these results demonstrate that

Indexed as

inflammatory responselipid metabolismnon-alcoholic fatty liver disease (NAFLD)Wnt/β-catenin signalingY-box binding protein 1 (YB-1)

Identifiers

PMID34988202
PMCPMC8667161
OpenAlexW4200594877

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.