ArticleAnnals of translational medicine2021
Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 2 citations in OpenAlex.
- NOTCH2NLA gene amplification is associated with poor prognosis in breast cancer.Discover oncology · 2026Article
- Comprehensive Exploration of NOTCH2NLA Across Cancers and Its Potential Roles in Prognosis and Immune System Interactions.Current medicinal chemistry · 2026Article
- Integrated analysis of differentially expressed genes implicated in ovarian cancer progression.Turkish journal of obstetrics and gynecology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAmong all gynecological malignancies, ovarian cancer (OC) is prone to recurrence, metastasis, and resistance, and has the highest mortality rate. Furthermore, China is about to face the risk of increased incidence of the disease. This study aimed to identify potential novel tumorigenesis and prognostic genes in OC.
methodsThe Genotype-Tissue Expression (GTEx) project and The Cancer Genome Atlas (TCGA) project were used to obtain mRNA sequencing datasets and clinical information to identify candidate genes critical to OC carcinogenesis and progression. The potential genes affecting OC were performed by comprehensive survival analysis, followed by external validation. Cell proliferation, wound healing, and transwell assays validated the effects of a potential gene on proliferation, migration, and invasion in the A2780 cell line. Observe xenograft formation in nude mice and use immunohistochemistry to determine the expression of epithelial-mesenchymal transition (EMT)-related proteins in xenograft tumors after gene silencing. Two-tailed Student's
resultsThe current study developed an eight-gene model for predicting the survival of patients with OC, in which
conclusionsThe study provided a novel view on the biological significance and function of
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.