Evidence map›Paper›PMID 34988149›Full record

ArticleAnnals of translational medicine2021

Body mass index is not associated with early onset cataract in the 45 and Up cohort study.

Jiaqing Zhang, Wei Wang, Guangyao Yang, Jason Ha, Xuhua Tan, Xianwen Shang, Zhuoting Zhu, Xiaotong Han, Zhenzhen Liu, Lei Zhang and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Jiaqing Zhang *State Key Laboratory of Ophthalmology, National Clinical Research Center, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Wei Wang *State Key Laboratory of Ophthalmology, National Clinical Research Center, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Guangyao Yang *Department of Ophthalmology, Municipal Hospital of Chifeng, Inner Mongolia Autonomous Region, Chifeng, China.
Jason HaCentre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
Xuhua TanState Key Laboratory of Ophthalmology, National Clinical Research Center, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Xianwen ShangCentre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
Zhuoting ZhuDepartment of Ophthalmology, Guangdong Academy of Medical Sciences, Guangdong Provincial People's Hospital, Guangzhou, China.
Xiaotong HanState Key Laboratory of Ophthalmology, National Clinical Research Center, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Zhenzhen LiuState Key Laboratory of Ophthalmology, National Clinical Research Center, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Lei ZhangCentre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
Mingguang HeState Key Laboratory of Ophthalmology, National Clinical Research Center, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Lixia LuoState Key Laboratory of Ophthalmology, National Clinical Research Center, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNCentre for Eye Research Australia · AUChifeng Municipal Hospital · CNGuangdong Provincial People's Hospital · CNMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBody mass index (BMI) has been reported to be associated with age-related cataract, whereas its impact on early onset cataract (EOC) remains unknown.

methodsA total of 73,007 individuals aged 45-55 years who had no previous cataract surgeries at baseline were enrolled from the population-based 45 and Up Study. BMI was calculated based on self-reported height and weight from the baseline questionnaire. Data on cataract surgeries were obtained from the Medicare Benefits Schedule database. EOC was defined as cataract surgically treated prior to 65 years of age. A Cox proportional hazards regression was used to assess the association between BMI and the incidence of EOC during the follow-up.

resultsA total of 1,764 participants underwent cataract surgery over 643,717 person-years of follow-up. No significant association was observed between BMI and EOC (P for trend 0.35). Among participants who drank 5 to 7 alcoholic drinks per week, a 73% and 27% reduction in the risk of EOC was observed in participants with a BMI of 18.5-19.99 and 25.0-27.49 kg/m

conclusionsNo association was identified between BMI and the incidence of EOC. Moderate alcohol intake may be protective against EOC.

Indexed as

45 and Up StudyAustraliancohortEarly-onset cataractrisk factor

Identifiers

PMID34988149
PMCPMC8667097
OpenAlexW3208860646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.