Evidence map›Paper›PMID 34988063›Full record

ReviewFrontiers in chemistry2021

Engineering Electrospun Nanofibers for the Treatment of Oral Diseases.

Yuanfei Wang, Yingnan Liu, Xiaopei Zhang, Na Liu, Xixi Yu, Meihua Gao, Wanchun Wang, Tong Wu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  12. Article
  13. Nanotechnology applications in oral pathology: A scoping review.Journal of oral and maxillofacial pathology : JOMFP
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yuanfei WangQingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, China.
Yingnan LiuInstitute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, China.
Xiaopei ZhangInstitute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, China.
Na LiuInstitute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, China.
Xixi YuQingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, China.
Meihua GaoQingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, China.
Wanchun WangQingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, China.
Tong WuInstitute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, China.
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increase of consumption of high-sugar foods, beverages, tobacco, and alcohol, the incidence rate of oral diseases has been increasing year by year. Statistics showed that the prevalence of oral diseases such as dental caries, dental pulpal disease, and periodontal disease has reached as high as 97% in 2015 in China. It is thus urgent to develop functional materials or products for the treatment of oral diseases. Electrospinning has been a widely used technology that is capable of utilizing polymer solution to generate micro/nano fibers under an appropriate high voltage condition. Owing to their excellent structures and biological performances, materials prepared by electrospinning technology have been used for a wide range of oral-related applications, such as tissue restoration, controlled drug release, anti-cancer, etc. In this regard, this article reviews the application and progress of electrospun nanofibers to various oral diseases in recent years. Firstly, engineering strategies of a variety of nanofiber structures together with their resultant functions will be introduced. Then, biological functions of electrospun nanofibers as well as their applications in the treatment of oral diseases are summarized and demonstrated. Finally, the development viewpoint of functional nanofibers is prospected, which is expected to lay the foundation and propose the direction for further clinical application.

Indexed as

biofunctionselectrospun nanofibersoral diseasesstructurestranslational application

Identifiers

PMID34988063
PMCPMC8721107
OpenAlexW4200062084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.