ReviewCureus2021
The Evolution of Fibromyalgia, Its Concepts, and Criteria.
Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Management of Juvenile Fibromyalgia: A Level I Evidence-Based Systematic Review.Medical sciences (Basel, Switzerland) · 2025Pooled it
- Pooled it
- Efficacy and mechanism of supervised adapted physical activity on quality of life for patients with fibromyalgia: single-center, prospective, randomised clinical and neuroimaging study.Scientific reports · 2026Trial
- Targeted limbic self-neuromodulation for alleviating central sensitization symptoms in fibromyalgia.BMC medicine · 2025Trial
- The Impact of Standard Care Versus Intrinsic Relaxation at Home on Physiological Parameters in Patients with Fibromyalgia: A Comparative Cohort Study from Romania.Medicina (Kaunas, Lithuania) · 2025Trial
- New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study.Arthritis care & research · 2026Article
- Prevalence and predictors of fibromyalgia symptoms in an academic setting: a cross-sectional study.BMC rheumatology · 2025Article
- Trauma and psychological impact in fibromyalgia and other central sensitization syndromes: the role of anxiety and pain acceptance.BMC psychology · 2025Article
- Fecal Microbiome in Women With Fibromyalgia: Functional Composition and Symptom Correlations.ACR open rheumatology · 2025Article
- Personality Assessment Inventory in Fibromyalgia: Links to Functional, Physical-Somatic, and Emotional Impact.European journal of investigation in health, psychology and education · 2025Article
- The Psychological Benefits of Forest Bathing in Individuals with Fibromyalgia and Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Pilot Study.Healthcare (Basel, Switzerland) · 2025Article
- Serum choline, leptin and interleukin-6 levels in fibromyalgia syndrome-induced pain: a case-control study.BMC musculoskeletal disorders · 2025Article
- Exploring patient activation and self-management experiences in adults with fibromyalgia: a qualitative evidence synthesis.Rheumatology advances in practice · 2025Review
- Mitochondrial function in patients affected with fibromyalgia syndrome is impaired and correlates with disease severity.Scientific reports · 2024Article
- Psychological Features of Fibromyalgia in the Psychological Health Services.Behavioral sciences (Basel, Switzerland) · 2024Article
- Physiotherapists' adherence to Clinical Practice Guidelines in fibromyalgia: a cross-sectional online survey.Rheumatology international · 2024Article
- Comparative Efficacy of Neuromodulation and Structured Exercise Program on Autonomic Modulation in Fibromyalgia Patients: Pilot Study.Journal of clinical medicine · 2024Article
- Hierarchical Clustering Applied to Chronic Pain Drawings Identifies Undiagnosed Fibromyalgia: Implications for Busy Clinical Practice.The journal of pain · 2024Observational
- Automated characterization and detection of fibromyalgia using slow wave sleep EEG signals with glucose pattern and D'hondt pooling technique.Cognitive neurodynamics · 2024Article
- Unraveling the Complex Web of Fibromyalgia: A Narrative Review.Medicina (Kaunas, Lithuania) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibromyalgia developed in the 1950s from a substrate of difficult to explain regional and widespread pain mixed with symptoms of psychosocial distress. Controversies regarding psychological issues were common. Multiple criteria arose to define the disorder, but each identified a different set of patients. The identification of widespread pain as a criterion changed the nature of the disorder by effectively eliminating regional pain as a component condition. The easy-to-measure and relatively reliable widespread pain criterion then came to define the disorder. In the primary care community, diagnostic criteria were largely ignored, and a substantial fraction of diagnosed patients with lower pain scores, particularly women and those with high non-pain symptom scores, were diagnosed. Non-pain symptoms were added back to the fibromyalgia definition and criteria in 2010. Recognition grew that fibromyalgia fit the description of a functional somatic disorder. The idea of fibromyalgia as a primary pain disorder with a neurobiological basis contended with fibromyalgia as a broader biopsychosocial disorder. It is increasingly recognized that fibromyalgia represents a dimensional, non-binary condition and that features of fibromyalgia extend to persons who do not satisfy the criteria. Severity assessments are now available but rarely used. The course of fibromyalgia is not well studied, and improvement and remission criteria have not been successfully defined. The future of fibromyalgia as a discrete disorder remains uncertain as features of fibromyalgia are increasingly observed in patients with multiple different medical conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.