Evidence map›Paper›PMID 34987900›Full record

ReviewCureus2021

Hereditary Hemochromatosis: A Cardiac Perspective.

Pranay K Joshi, Saawan C Patel, Devarashetty Shreya, Diana I Zamora, Gautami S Patel, Idan Grossmann, Kevin Rodriguez, Mridul Soni, Ibrahim Sange

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. [Chinese guidelines for the diagnosis and treatment of hereditary hemochromatosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Guideline
  2. Article
  3. Article
  4. Article
  5. Review
  6. BMJ open · 2024
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Pranay K JoshiInternal Medicine, B.J. Medical College, Ahmedabad, IND.
Saawan C PatelInternal Medicine, Pramukhswami Medical College, Karamsad, IND.
Devarashetty ShreyaInternal Medicine, Gandhi Medical College, Secunderabad, Hyderabad, IND.
Diana I ZamoraGeneral Medicine, Universidad de Ciencias Médicas Andrés Vesalio Guzman, San José, CRI.
Gautami S PatelInternal Medicine, Pramukhswami Medical College, Karamsad, IND.
Idan GrossmannResearch, Medical University of Silesia, Katowice Faculty of Medical Sciences, Katowice, POL.
Kevin RodriguezResearch, Universidad Americana Managua (UAM), Managua, NIC.
Mridul SoniPediatric Gastroenterology, Shri Lal Bahadur Shastri Government Medical College and Hospital, Mandi, IND.
Ibrahim SangeResearch, K. J. Somaiya Medical College, Mumbai, IND.
Medical University of Silesia · PLGovernment Medical College and Hospital · INGandhi Medical College & Hospital · INK J Somaiya Medical College · INLa American University · NIPramukhswami Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hereditary hemochromatosis (HH) is a common genetic metabolic disorder characterized by excessive iron absorption and elevated serum iron levels, which accumulate in various organs, such as the heart, pancreas, gonads, and damage these organs. There are only a few articles and clinical studies describing the characteristics of cardiac involvement in HH along with the significance of early diagnosis and management in preventing complications. In this review article, we have reviewed multiple pieces of literature and gathered available information regarding the subject. We compiled the data to investigate the importance of early detection of symptoms, regular monitoring, and prompt management with strict adherence to reverse or prevent complications. This article has reviewed different aspects of cardiac hemochromatosis, such as pathogenesis, clinical presentation, diagnosis, and management. Recognition of early symptoms, diagnosis of cardiac involvement with various modalities, and implementation of early treatment are essentially the foundation of better outcomes in HH.

Indexed as

cardiac arrhythmiacardiac hemochromatosishereditary hemochromatosisiron overload cardiomyopathyprimary iron overload

Identifiers

PMID34987900
PMCPMC8716004
OpenAlexW3214913454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.