Evidence map›Paper›PMID 34987798›Full record

ArticleMolecular and clinical oncology2022

An artificial intelligence-assisted diagnostic system improves the accuracy of image diagnosis of uterine cervical lesions.

Yu Ito, Ai Miyoshi, Yutaka Ueda, Yusuke Tanaka, Ruriko Nakae, Akiko Morimoto, Mayu Shiomi, Takayuki Enomoto, Masayuki Sekine, Toshiyuki Sasagawa and 9 more

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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  5. Advances in artificial intelligence for the early detection of cervical cancer in adult women: a scoping review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Yu ItoDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 567-0871, Japan.
Ai MiyoshiDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 567-0871, Japan.
Yutaka UedaDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 567-0871, Japan.
Yusuke TanakaDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 567-0871, Japan.
Ruriko NakaeDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 567-0871, Japan.
Akiko MorimotoDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 567-0871, Japan.
Mayu ShiomiDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 567-0871, Japan.
Takayuki EnomotoDepartment of Obstetrics and Gynecology, Niigata University Graduate School of Medicine, Chuo-ku, Niigata 951-8520, Japan.
Masayuki SekineDepartment of Obstetrics and Gynecology, Niigata University Graduate School of Medicine, Chuo-ku, Niigata 951-8520, Japan.
Toshiyuki SasagawaDepartment of Obstetrics and Gynecology, Kanazawa Medical University, Uchinada, Ishikawa 920-0293, Japan.
Kiyoshi YoshinoDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8556, Japan.
Hiroshi HaradaDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8556, Japan.
Takafumi NakamuraDepartment of Obstetrics and Gynecology, Kawasaki Medical University, Kurashiki, Okayama 701-0192, Japan.
Takuya MurataDepartment of Obstetrics and Gynecology, Kawasaki Medical University, Kurashiki, Okayama 701-0192, Japan.
Keizo HiramatsuHiramatsu Obstetrics and Gynecology Clinic, Kishiwada-shi, Osaka 583-0024, Japan.
Junko SaitoSaito Women Clinic, Yodogawa-ku, Osaka 532-0003, Japan.
Junko YagiLadies Clinic Yagi, Senboku-gunn, Osaka 595-0805, Japan.
Yoshiaki TanakaMaki Ladies Clinic, Ibaraki-shi, Osaka 567-0031, Japan.
Tadashi KimuraDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 567-0871, Japan.
Osaka University · JPKawasaki Medical School · JPNiigata University · JPUniversity of Occupational and Environmental Health Japan · JPKanazawa Medical University · JPKishiwada City Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study created an artificial intelligence (AI)-automated diagnostics system for uterine cervical lesions and assessed the performance of these images for AI diagnostic imaging of pathological cervical lesions. A total of 463 colposcopic images were analyzed. The traditional colposcopy diagnoses were compared to those obtained by AI image diagnosis. Next, 100 images were presented to a panel of 32 gynecologists who independently examined each image in a blinded fashion and diagnosed them for four categories of tumors. Then, the 32 gynecologists revisited their diagnosis for each image after being informed of the AI diagnosis. The present study assessed any changes in physician diagnosis and the accuracy of AI-image-assisted diagnosis (AISD). The accuracy of AI was 57.8% for normal, 35.4% for cervical intraepithelial neoplasia (CIN)1, 40.5% for CIN2-3 and 44.2% for invasive cancer. The accuracy of gynecologist diagnoses from cervical pathological images, before knowing the AI image diagnosis, was 54.4% for CIN2-3 and 38.9% for invasive cancer. After learning of the AISD, their accuracy improved to 58.0% for CIN2-3 and 48.5% for invasive cancer. AI-assisted image diagnosis was able to improve gynecologist diagnosis accuracy significantly (P<0.01) for invasive cancer and tended to improve their accuracy for CIN2-3 (P=0.14).

Indexed as

artificial intelligencecervical cancercervical intraepithelial neoplasiacolposcopydeep learningimage diagnosis

Identifiers

PMID34987798
PMCPMC8719259
OpenAlexW4200419445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.