ReviewClinical kidney journal2021
Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches.
Review in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Chronic kidney disease-associated pruritus and patient-centred outcomes: a systematic review.Journal of nephrology · 2025Pooled it
- Comparative efficacy of acupuncture point stimulation treatments for dialysis patients with uremic pruritus: a systematic review and network meta-analysis.Frontiers in neurology · 2024Pooled it
- Deciding between conservative kidney management and dialysis in older people with kidney failure: a narrative review.Clinical kidney journal · 2026Review
- Development and evaluation of a clinical dashboard for nephrology inpatients: a pilot study.BMC medical informatics and decision making · 2026Article
- Difelikefalin in Chinese patients with chronic kidney disease-associated pruritus.Clinical kidney journal · 2026Article
- Combined effect of atopic dermatitis and chronic kidney disease on overall and cardiovascular disease mortality.Scientific reports · 2026Article
- Uremic Pruritus in Hemodialysis: Mechanisms, Burden, and Emerging Therapies.Journal of clinical medicine · 2026Review
- Essential oil massage and incident chronic kidney disease-associated pruritus in maintenance hemodialysis patients without baseline pruritus: a prospective non-concurrent before-and-after study.Frontiers in medicine · 2026Article
- Association of Obesity and Body Composition and Hospitalization Risk with Infection in the CRIC Study.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Real-world safety of difelikefalin for chronic kidney disease-associated pruritus: initial insights from a European managed access programme.Clinical kidney journal · 2025Article
- Pruritus in Palliative Care: A Narrative Review of Essential Oil-Based Strategies to Alleviate Cutaneous Discomfort.Diseases (Basel, Switzerland) · 2025Review
- Pruritus in Uremic Patients: Approaches to Alleviating a Common Symptom in Chronic Kidney Disease.Life (Basel, Switzerland) · 2025Review
- CKD-associated pruritus in haemodialysis: a road map for diagnosis and treatment.Clinical kidney journal · 2025Review
- Real-world use of difelikefalin in hemodialysis patients at a large dialysis organization in the United States: a retrospective database study.BMC nephrology · 2025Article
- CKD-Associated Pruritus is Associated with Greater Use of Antidepressants and Anti-pruritus Medications.Advances in therapy · 2025Article
- Cutaneous Manifestations in Patients on Hemodialysis and Assessment of the Changes in Quality of Life After 12 Weeks of Treatment by a Dermatologist.Journal of Korean medical science · 2024Article
- Chronic Kidney Disease-Associated Pruritus Burden: A Patient Survey Study.Kidney medicine · 2024Article
- Chronic kidney disease-associated pruritus and quality of life with difelikefalin treatment: aClinical kidney journal · 2024Article
- Chronic kidney disease-associated pruritus (CKD-aP) is associated with worse quality of life and increased healthcare utilization among dialysis patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Delivering Personalized, Goal-Directed Care to Older Patients Receiving Peritoneal Dialysis.Kidney diseases (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic kidney disease (CKD)-associated pruritus (CKD-aP) is an underdiagnosed yet severely distressing condition that impacts 60% of patients on dialysis and many nondialysis patients with Stages 3-5 CKD. However, despite its high prevalence, there are currently limited treatment options available for these patients and a lack of treatment guidelines for clinicians. In this manuscript, we reviewed the available literature in order to evaluate the current management and treatment options for CKD-aP, including dialysis management, topical treatments, gabapentinoids, opioids and alternative medicine. We also review the available data on CKD-aP treatments in development and propose new guidelines for managing patients with CKD-aP.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.