Evidence map›Paper›PMID 34987771›Full record

ArticleF1000Research2021

The impact of testing and treatment on the dynamics of Hepatitis B virus.

Olajumoke Oludoun, Olukayode Adebimpe, James Ndako, Michael Adeniyi, Oluwakemi Abiodun, Babatunde Gbadamosi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olajumoke OludounPhysical sciences, Landmark University, Omu Aran, Kwara State, Nigeria.ORCID 0000-0003-4083-2138
Olukayode AdebimpePhysical Sciences, Landmark University, Omu Aran, Kwara, Nigeria.
James NdakoBiological Sciences, Landmark University, Omu Aran, Kwara, Nigeria.ORCID 0000-0002-2576-8230
Michael AdeniyiMathematics, Lagos State Polytechnic, Lagos, Lagos, Nigeria.
Oluwakemi AbiodunPhysical Sciences (Mathematics Programme), Landmark University, Omu Aran, Kwara, Nigeria.ORCID 0000-0003-3995-6889
Babatunde GbadamosiComputer Science, Landmark University, Omu Aran, Kwara, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the intervention of WHO on vaccination for reducing the spread of Hepatitis B Virus (HBV), there are records of the high prevalence of HBV in some regions. In this paper, a mathematical model was formulated to analyze the acquisition and transmission process of the virus with the view of identifying the possible way of reducing the menace and mitigating the risk of the virus. The models' positivity and boundedness were demonstrated using well-known theorems. Equating the differential equations to zero demonstrates the equilibria of the solutions i.e., the disease-free and endemic equilibrium. The next Generation Matrix method was used to compute the basic reproduction number for the models. Local and global stabilities of the models were shown via linearization and Lyapunov function methods respectively. The importance of testing and treatment on the dynamics of HBV were fully discussed in this paper. It was discovered that testing at the acute stage of the virus and chronic unaware state helps in better management of the virus.

Indexed as

Hepatitis BHepatitis B virusHumansModels, TheoreticalPrevalenceVaccinationEquilibria of solutionsLinearizationlocal and global stabilities.Lyapunov functionsNext generation matrix: Positivity and boundedness of solutions

Identifiers

PMID34987771
PMCPMC8686325

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.