ArticleInternational journal of organ transplantation medicine2021
Thin Split Thickness Skin Grafting on Human Acellular Dermal Matrix Scaffold for the Treatment of Deep Burn Wounds.
Article in International journal of organ transplantation medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- ECM-Preserving Decellularization of Dermis via Subtle Cell Membrane Disruption Induced by Subcritical Dimethyl Ether.ACS omega · 2025Article
- Indicators of the number of surgeries and severity in pediatric patients with severe burns: a retrospective comparative study.Pediatric surgery international · 2025Article
- Decellularized Extracellular Matrices for Skin Wound Treatment.Materials (Basel, Switzerland) · 2025Review
- Advanced biomaterial strategies for overcoming age-associated wound healing impairments.APL bioengineering · 2025Review
- Cell-matrix feedback controls stretch-induced cellular memory and fibroblast activation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Next-Generation Biomaterials for Wound Healing: Development and Evaluation of Collagen Scaffolds Functionalized with a Heparan Sulfate Mimic and Fibroblast Growth Factor 2.Journal of functional biomaterials · 2025Article
- Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2025Review
- Comparison between artificial dermis with split-thickness skin graft and full-thickness skin graft for reconstruction of joint-involved burn wounds: A retrospective review from a tertiary burn centre.International wound journal · 2025Article
- Expansion limits of meshed split-thickness skin grafts.Acta biomaterialia · 2025Article
- Decellularization techniques of human foreskin for tissue engineering application.Physiological research · 2023Article
- Copper-Epigallocatechin Gallate Enhances Therapeutic Effects of 3D-Printed Dermal Scaffolds in Mitigating Diabetic Wound Scarring.ACS applied materials & interfaces · 2023Article
- Negative Pressure Wound Therapy (NPWT) after Hybrid Reconstruction of Occipital Pressure Sore Using Local Flap and Skin Graft.Medicina (Kaunas, Lithuania) · 2023Article
- Sustainable Approach of Functional Biomaterials-Tissue Engineering for Skin Burn Treatment: A Comprehensive Review.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Recent advances in decellularized biomaterials for wound healing.Materials today. Bio · 2023Review
- Article
- Membranous Extracellular Matrix-Based Scaffolds for Skin Wound Healing.Pharmaceutics · 2021Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUse of AlloDerm™ is highly suggested for the treatment of deep burns and burn sequela reconstruction. Scar formation and contracture are recognized as long-term consequences of split-thickness skin autografting, which is applied for full-thickness burn injuries. Mature fibroblasts, in the absence of dermis, seem to secrete collagen in the reformed scar pattern.
objectiveTo process AlloDerm™ from fresh allograft and use it as a dermal substitute for covering deep wounds in burn patients and evaluate its effectiveness.
methodsIn this case-series, 7 patients with deep burn wounds involving different locations on the body surface were exposed to combined AlloDerm™ (processed from fresh human allograft) with thin split thickness skin autograft on it. On the 5
resultsThe results showed excellent graft take, good elasticity, acceptable thickness, and little contracture and scarring according to fix surgeon assessment in 6 patients. Graft rejection happened only in one patient with chronic electrical injury.
conclusionAlloDerm™ derived from cadaver skin and combination of it with thin split thickness skin auto grafting constitute a cost-effective and favorable option for the treatment of deep burn wounds in our center, considering the increased tendency of the population towards organ donation in the event of brain death.
Indexed as
Identifiers
34987732PMC8717875W3137081235What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.