Evidence map›Paper›PMID 34987668›Full record

ArticleJournal of children's orthopaedics2021

The utility of echocardiography in paediatric patients with musculoskeletal infections and bacteremia.

Andromahi Trivellas, Dane Brodke, Vivian Hu, Annabelle de St Maurice, Paul Krogstad, Mauricio Silva, Rachel M Thompson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of children's orthopaedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Andromahi TrivellasDepartment of Orthopaedic Surgery, University of California, Los Angeles, California, United States.ORCID https://orcid.org/0000-0002-3002-1764
Dane BrodkeDepartment of Orthopaedic Surgery, University of California, Los Angeles, California, United States.
Vivian HuDavid Geffen School of Medicine University of California, Los Angeles, California, United States.ORCID https://orcid.org/0000-0002-5548-9283
Annabelle de St MauriceDavid Geffen School of Medicine University of California, Los Angeles, California, United States.
Paul KrogstadDavid Geffen School of Medicine University of California, Los Angeles, California, United States.
Mauricio SilvaRenee Meyer Luskin Children's Clinic, Orthopaedic Institute for Children, University of California, Los Angeles, California, United States.
Rachel M ThompsonRenee Meyer Luskin Children's Clinic, Orthopaedic Institute for Children, University of California, Los Angeles, California, United States.
University of California, Los Angeles · USOrthopaedic Institute for Children · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe clinical utility of echocardiography in the setting of a positive blood culture in paediatric patients presenting with osteomyelitis (OM) and/or septic arthritis (SA).

methodsRetrospective review between 2013 and 2019: Patients < 18 years with OM, SA or combined infection (OM+SA) were included. Patients were excluded for immunodeficiency, loss of follow-up or penetrating infection. Charts with positive blood cultures were reviewed for echocardiography on that admission. Demographic variables were compared utilizing the Student's

resultsOf 157 patients with OM, SA or combined infection, 44 had a positive blood culture. In all, 26 had an echocardiogram, and none showed endocarditis. Echocardiography was independently associated with a 6.2-day length of stay increase. WBC count and surgical intervention demonstrated a trend toward significance in length of stay, with each WBC unit increase associated with a 0.53-day increase. Surgical intervention was associated with an average 6.3-day length of stay decrease.

conclusionNo patient had a positive echocardiogram, and no changes in management were initiated. However, an echocardiogram increased stay by 6.2 days. In addition to costs associated with increased stay, patients were billed between $1460 and $1700 per echocardiogram. The utility of echocardiograms in the setting of bacteremia associated with musculoskeletal infections in the paediatric population should be re-examined, and guidelines should be updated to reflect the cost-benefit analysis. LEVEL OF EVIDENCE: III.

Indexed as

bacteremiaechocardiographyinfectious diseasemusculoskeletal infectionosteomyelitis

Identifiers

PMID34987668
PMCPMC8670541
OpenAlexW3210937003

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.