Evidence map›Paper›PMID 34987644›Full record

ArticleTheranostics2022

Driver mutations of intrahepatic cholangiocarcinoma shape clinically relevant genomic clusters with distinct molecular features and therapeutic vulnerabilities.

Xiang-Yu Wang, Wen-Wei Zhu, Zheng Wang, Jian-Bo Huang, Sheng-Hao Wang, Fu-Mao Bai, Tian-En Li, Ying Zhu, Jing Zhao, Xin Yang and 8 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Present and future of liver transplantation for cholangiocellular carcinoma: moving toward personalized multiparametric transplantability patterns.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Review
  5. Cholangiocarcinoma 2026: status quo, unmet needs and priorities.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Oncogenic gene fusions in cancer: from biology to therapy.Signal transduction and targeted therapy · 2025
    Review
  13. Review
  14. Review
  15. Review
  16. The role of mesenchymal cells in cholangiocarcinoma.Disease models & mechanisms · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Xiang-Yu WangDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Wen-Wei ZhuDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Zheng WangDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Jian-Bo HuangDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Sheng-Hao WangDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Fu-Mao BaiDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Tian-En LiDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Ying ZhuDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Jing ZhaoDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Xin YangDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Lu LuDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Ju-Bo ZhangCancer Metastasis Institute, Fudan University, Shanghai, China.
Hu-Liang JiaDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Qiong-Zhu DongDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Jin-Hong ChenDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Jesper B AndersenBiotech Research and Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark.
Dan YeDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Lun-Xiu QinDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Fudan University · CNHuashan Hospital · CNFudan University Shanghai Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedBile Duct NeoplasmsBiomarkers, TumorCholangiocarcinomaCohort StudiesFemaleHumansMaleMiddle AgedMutationPrognosisBiomarkers, TumorDriver mutationGenome sequencingICC diversity.

Identifiers

PMID34987644
PMCPMC8690927
OpenAlexW3212098250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.